Which antidepressants are best for fibromyalgia?

Antidepressants used to treat fibromyalgia include:

tricyclic antidepressants, such as amitriptyline.
serotonin-noradrenaline reuptake inhibitors (SNRIs), such as duloxetine and venlafaxine.
selective serotonin reuptake inhibitors (SSRIs), such as fluoxetine (Prozac) and paroxetine.

What is the safest SNRI?

Seniors. SNRIs are generally safe and effective for use in older adults. Effexor XR (venlafaxine) and Cymbalta (duloxetine) are commonly prescribed in this population for the treatment of depression.

What are the most common SNRIs?

The Food and Drug Administration (FDA) has approved these SNRIs to treat depression:

Desvenlafaxine (Pristiq)
Duloxetine (Cymbalta) — also approved to treat anxiety and certain types of chronic pain.
Levomilnacipran (Fetzima)
Venlafaxine (Effexor XR) — also approved to treat certain anxiety disorders and panic disorder.

Which SNRI has the least side effects?

Antidepressants with the lowest rate of sexual side effects include: Bupropion (Wellbutrin XL, Wellbutrin SR)

Is Cymbalta better than Effexor?

Is Cymbalta or Effexor more effective? The effectiveness of Cymbalta or Effexor depends on the condition being treated. Very few studies have directly compared Cymbalta and Effexor. However, when compared to placebo, Cymbalta and Effexor are both more effective for treating conditions like major depression.

Is Cymbalta SSRI or SNRI?

Cymbalta is classified in a group of medications called SNRIs (serotonin-norepinephrine reuptake inhibitors). They work by increasing the levels of serotonin and norepinephrine in the brain. Prozac is part of a group of drugs called SSRIs (selective serotonin reuptake inhibitors).

What is Wellbutrin classified as?

Wellbutrin may be used alone or with other medications. Wellbutrin belongs to a class of drugs called Antidepressants, Dopamine Reuptake Inhibitors, Antidepressants, Other, Smoking Cessation Aids.