What causes dystrophic calcification?
Dystrophic calcification (DC) is the calcification occurring in degenerated or necrotic tissue, as in hyalinized scars, degenerated foci in leiomyomas, and caseous nodules. This occurs as a reaction to tissue damage, including as a consequence of medical device implantation.
What are the types of pathologic calcification?
PATHOLOGIC CALCIFICATION
- Definition – Abnormal deposition of calcium salts in the tissue other than osteoid or enamel.
- Two types of pathologic calcifications are-
- Dystrophic calcification.
- Metastatic calcification.
What is calcification pathology?
By definition, pathologic calcification refers to the deposition of calcium phosphates (CaP) or other calcific salts at sites, which would not normally have become mineralized. Abnormal accumulation can occur in areas of tissue damage (dystrophic calcification), in hypercalcemic or hyperparathyroid states (2).
Is dystrophic calcification normal?
Dystrophic soft tissue calcification is a type of soft-tissue calcification, which occurs in damaged or necrotic tissue, while the serum level of calcium and phosphorus are normal. It may progress to ossification, in which case a cortical and trabecular bone pattern is visible.
What is dystrophic ossification?
Dystrophic calcification (DC) is the abnormal appearance of calcified deposits in degenerating tissue, often associated with injury. Extensive DC can lead to heterotopic ossification (HO), a pathological condition of ectopic bone formation.
What is dystrophic calcinosis?
Dystrophic calcinosis is the abnormal collection of calcium salts in or under the skin and in muscles or tendons, even when levels of calcium in the blood are normal. It occurs in some patients with dermatomyositis.
What is the difference between dystrophic and metastatic calcification?
The mechanism of calcification in the viscera is categorized into two groups. Metastatic calcification with hypercalcemia occurs when calcium deposits in previously normal tissue whereas dystrophic calcification occurs in previously damaged tissue.
Is dystrophic calcification painful?
The nodules can vary in shape and size and can be painful leading to functional impairment. The lesions in dystrophic calcification are localized based on the underlying disease.
What does dystrophic ossification mean?
Dystrophic calcification can be defined as a calcification that occurs in degenerated or necrotic tissue. It is associated with multiple clinical conditions, such as collagen vascular diseases.
What is dystrophic calcification of the breast?
Dystrophic Breast Calcification. Radiographers commonly find breast calcifications on a mammogram, and dystrophic calcification is a certain type of calcification. Specialists consider dystrophic calcification to be a benign (non-cancerous) finding.