What is the groove sign eosinophilic fasciitis?
Groove sign is a characteristic finding of eosinophilic fasciitis, consisting of a depression along the course of the superficial veins, more marked on elevation of the affected limb.
What are the signs and symptoms of eosinophilic fasciitis?
Symptoms
- Tenderness and swelling of the skin on the arms, legs, or sometimes the joints (most often on both sides of the body)
- Arthritis.
- Carpal tunnel syndrome.
- Muscle pain.
- Thickened skin that looks puckered.
How is eosinophilic fasciitis diagnosed?
A diagnosis of eosinophilic fasciitis is confirmed by surgical removal and microscopic evaluation (biopsy) of affected tissue. A biopsy demonstrates thickening and inflammation of fascia and surrounding tissue.
What does eosinophilic fasciitis do to the body?
Eosinophilic fasciitis causes inflammation of the tissues beneath the skin as well as sometimes in the skin. This leads to symptoms of swelling, stiffness, warmth, and pain of the involved area. Occasionally, there is discoloration of the skin over the tissues affected and the skin can appear thicker than normal.
What is Shulman syndrome?
Eosinophilic fasciitis, also called Shulman syndrome, is a rare variant of scleroderma or deep form of morphoea involving the subcutis and fascia of the skin characterised by fascial thickening with an eosinophilic tissue infiltrate and peripheral eosinophilia.
How do you diagnose scleroderma?
To diagnose scleroderma, a doctor usually begins by asking you about your symptoms, health, and medical history. The doctor will also examine your skin for signs of hardening and thickening. If you have hard, thickened skin, a dermatologist may perform a skin biopsy to help diagnose you.
Is eosinophilic fasciitis an autoimmune disease?
What is the outcome for eosinophilic fasciitis? Eosinophilic fasciitis can be associated with or progress to morphoea or other autoimmune connective tissue disorders in 20–30% of cases. Associated haematological disorders such as aplastic anaemia and lymphoma have been reported.
Why does induration happen?
Skin induration is a deep thickening of the skin that can result from edema, inflammation, or infiltration, including by cancer. Diagnosis of skin induration is made by palpation (feeling the area) and assessing whether the raised area has a hard, resistant feeling.
Is eosinophilic fasciitis a connective tissue disease?
The eosinophilic fasciitis (EF) is a rare connective tissue disease characterized by symmetrical and painful swelling with a progressive induration and thickening of the skin and soft tissues.