What is DMSA used for?
Dimercaptosuccinic acid (DMSA), also called succimer, is a medication used to treat lead, mercury, and arsenic poisoning. When radiolabeled with technetium-99m, it is used in a number of types of diagnostic testing. A full course is 19 days of medications by mouth.
What are leads in medicine?
In medicine, a chemical compound that shows promise as a treatment for a disease and may lead to the development of a new drug. Thousands of compounds are tested in the laboratory to find a lead (“leading”) compound that may act on specific genes or proteins involved in a disease.
What is the half life of DMSA?
It is covalently bound to proteins in plasma, and the half-life of DMSA is <4 h in humans. Ten percent to 25% of an orally administered dose of DMSA is excreted in the urine; the majority within 24 h.
Is DMSA over the counter?
The products list DMSA (meso-2, 3-dimercaptosuccinic acid), as an active ingredient, which is contained in an FDA-approved prescription product indicated for the treatment of lead poisoning in children. FDA advises consumers to avoid all products offered over-the-counter (OTC) for chelation or detoxification.
Can I buy DMSA?
Simple to use and effective, DMSA is now available to buy in dietary supplement form, specifically formulated to contain 100 mg of DMSA per capsule.
Does DMSA damage the kidneys?
The DMSA renal (REE-nul) scan is a nuclear medicine test that gives detailed pictures of the kidneys. Nuclear medicine tests work through the use of a small amount of radioactive material called a radioisotope (RAY-dee-oh-EYE-so-tope). The radioisotope is safe and will not hurt your child.
What is a lead in a hospital?
Lead Registration Clerk Greets and makes patients comfortable while registering them for hospital services. Explains hospital policies including parking, personal items, and visitation.
Does DMSA make your urine smell?
DMSA may impart an unusual smell to the freshly-voided urine. This is not part of a toxic reaction to the chelating agent. In spite of these necessary caveats, DMSA is a safe and widely used agent.
What does MAG3 stand for?
A MAG3 scan is a nuclear medicine scan that allows your doctor to examine the function and drainage of your kidneys. MAG3 (which stands for Mercaptoacetyltriglycine) is a radiopharmaceutical that is injected into the bloodstream.
Is DMSA a prescription drug?
DMSA and EDTA are mainstream medications. A prescription version of DMSA — brand name Chemet — is used (rarely) to treat severe overdoses of lead.
Where does the word succinct come from?
Eventually, “succinct” was extended to the realm of insects, where it meant “supported by a band of silk around the middle” (as in “the succinct pupa of a butterfly”). Later, the word was applied to writings. A “succinct” piece of writing is “compressed” or “compact” and uses as few words as possible. Examples of succinct in a Sentence
What is succimer used for?
succimer A water-soluble chelator administered per os for heavy metal poisoning–eg, lead poisoning in children > 2.17 µmol/L–US: 45 µg/dl or adults with lead poisoning due to gunshot wounds. See Lead, Saturnine gout.
What is [Suk]Mer?
[suk´sĭmer] a chelating agentthat is an analogue of dimercaprol, administered orally in the treatment of heavy metal poisoning. A complex with technetium 99m is used in renal function testing. Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc.
What does succinct mean in fashion?
In its earliest uses succinct meant “confined” or “girded up,” and, as such, it was often used in reference to garments encircled by a band. Eventually, succinct was extended to the realm of insects, where it meant “supported by a band of silk around the middle” (as in “the succinct pupa of a butterfly”). Later, the word was applied to writings.