How much ondansetron is lethal?
16 Overdose is rare and no fatal dose has been established. The largest single dose reported was 145 mg (1.5 mg/kg).
What does too much ondansetron do?
What happens if I overdose on Ondansetron (Zofran)? Overdose symptoms may include sudden loss of vision, severe constipation, feeling light-headed, or fainting.
Can ondansetron cause death?
A report from the USA has linked Glaxo’s Zofran (ondansetron), an anti-emetic used in cancer chemotherapy treatment, to two deaths and a third non-fatal cardiac arrest.
What is the antidote for ondansetron?
There is no specific antidote for ondansetron overdose. Patients should be managed with appropriate supportive therapy.
Can I give my dog 4 mg of Zofran?
o Ondansetron (Zofran®) Dosage: 0.5-1 mg/kg orally up to three times a day, or 4 mg for a small dog and 8 mg for a large dog. Indication/s: This can also be an expensive medication. However, it is a great first-line or second-line treatment for dogs with mild to severe inappetence, nausea or vomiting.
How long does 4mg Zofran last?
The effects of Zofran (ondansetron) can last anywhere between 8 to 12 hours.
Can Zofran cause death?
Some of the reported cases were fatal, according to the drug’s label. The majority of the cases occurred in a post-anesthesia care unit or infusion center, but a Zofran overdose can also lead to serotonin syndrome.
How much ondansetron can you take in 24 hours?
The total dose over 24 hours (given as divided doses) must not exceed adult dose of 32 mg. a The intravenous dose must not exceed 8 mg.
How do I report ondansetron side effects to FDA?
You may report side effects to FDA at 1-800-FDA-1088. Usual Adult Dose of Ondansetron for Nausea/Vomiting — Chemotherapy Induced: -Recommended dose: 0.15 mg/kg IV, with the first dose (infused over 15 minutes) 30 minutes before the start of emetogenic chemotherapy and subsequent doses given 4 and 8 hours after the first dose.
How much ondansetron should I take for vomiting?
Usual Adult Dose of Ondansetron for Nausea/Vomiting — Postoperative: Oral:-Recommended dose: 16 mg orally 1 hour before the induction of anesthesia Parenteral:-Recommended dose: 4 mg IV (undiluted) immediately before induction of anesthesia or postoperatively (nausea and/or vomiting within 2 hours after surgery)
What kind of pill is ondansetron 4 mg?
Ondansetron Orally Disintegrating Tablets USP, 4 mg are white to off-white, round tablets debossed with ‘5’ on one side and ‘E’ on the other side with an embossed circular edge.
What is the molecular formula of ondansetron?
The molecular formula is C18H19N3O representing a molecular weight of 293.4 g/mol. Ondansetron is a white to off-white powder. Each 4 mg ondansetron orally disintegrating tablet, USP for oral administration contains 4 mg ondansetron base. Each 8 mg ondansetron orally disintegrating tablet, USP for oral administration contains 8 mg ondansetron base.