What is indocyanine green angiography used for?
Indocyanine Green Angiography (ICG) is a diagnostic procedure that uses ICG dye to examine the blood flow in the CHOROID – the layer of blood vessels which lies underneath the retina.
What are the phases of fluorescein angiography?
Fluorescein angiograms progress through five phases: pre-arterial (choroidal flush), arterial, arteriovenous, venous and late recirculation.
How is indocyanine green excreted?
ICG is rapidly extracted by the liver without modifications and nearly exclusively excreted by the liver appearing unconjugated in the bile about 8 min after injection, depending on liver vascularization and function [13, 17].
Which dye is used in fundus fluorescein angiography?
Indocyanine green angiography (ICG) The dye used is Indocyanine green which fluoresces in Infra-red spectrum of light. This property enables imaging even through blood, fluid or pigmentation.
Does ICG contain iodine?
Grade 3 reactions are life threatening and typically require an ICU admission. ICG contains sodium iodide and, according to the manufacturer, it should be used with caution in patients who have a history of allergy to iodides because of the risk of anaphylaxis.
When are ICG angiography images taken?
Images are usually taken at intervals at least up to thirty minutes, and perhaps as long as an hour after the injection. ICG angiography is similar to fluorescein angiography.
When is fluorescein angiography indicated?
Fluorescein angiography looks at the blood flow to your retina and the rest of your eye. Your eye doctor may recommend it for reasons like: To diagnose, confirm, or rule out a retinal disease, including eye melanoma (cancer) To figure out if an eye treatment is working.
How long does indocyanine green stay in your system?
Because of the plasma protein binding, ICG stays for up to 20 to 30 minutes in the vessels (intravasally). When the eye is examined, it thus stays for a long time in tissues with a higher blood flow, such as the choroid and the blood vessels of the retina.
What is ICG in laparoscopy?
Real-time intraoperative imaging using indocyanine green (ICG) might reduce the risk of bile duct injury by improving visualization of the biliary tree during laparoscopic cholecystectomy. We compared the outcomes of laparoscopic cholecystectomy in patients with and without real-time ICG.
What can fluorescein angiography detect?
What Is Fluorescein Angiography For? Fluorescein angiography looks at the blood flow to your retina and the rest of your eye. Your eye doctor may recommend it for reasons like: To diagnose, confirm, or rule out a retinal disease, including eye melanoma (cancer)
What is the purpose of fundus fluorescein angiography?
A fluorescein angiography is a medical procedure in which a fluorescent dye is injected into the bloodstream. The dye highlights the blood vessels in the back of the eye so they can be photographed. This test is often used to manage eye disorders.