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What does the monoamine theory of depression state?

What does the monoamine theory of depression state?

The monoamine hypothesis of depression predicts that the underlying pathophysiologic basis of depression is a depletion in the levels of serotonin, norepinephrine, and/or dopamine in the central nervous system.

What is evidence in Favour of the monoamine theory of depression?

Another piece of evidence in support of the Monoamine Hypothesis is that levels of 5-HT, as measured by its metabolites, seem to be correlated with depression. For example, patients who have low levels of a 5-HT metabolite were found to be more likely to have committed suicide.

What is the main theory of depression?

According to Seligman’s learned helplessness theory, depression occurs when a person learns that their attempts to escape negative situations make no difference. As a consequence they become passive and will endure aversive stimuli or environments even when escape is possible.

What factors predict depression?

We know that a range of contributing factors can lead to clinical depression.

  • genetics (family history)
  • biochemical factors (brain chemistry)
  • illness.
  • personality style.
  • ageing.
  • long-term pressures such as abusive relationships, bullying and work stress.
  • stressful or traumatic events.

Is the monoamine hypothesis true?

Conclusion. It is asserted that the monoamine hypothesis, which claims that low synaptic levels of monoamines are a primary etiology of disease, is not a valid primary reference point for understanding chronic electrical dysfunction related to the centrally acting monoamines.

What is the cognitive theory of depression?

Cognitive theories of depression posit that people’s thoughts, inferences, attitudes, and interpretations, and the way in which they attend to and recall events, can increase their risk for the development and recurrence of depressive episodes.

What is the psychoanalytic theory of depression?

Psychoanalysts historically believed that depression was caused by anger converted into self-hatred (“anger turned inward”). A typical scenario regarding how this transformation was thought to play out may be helpful is further explaining this theory.