What does sodium iodide in acetone test for?

What does sodium iodide in acetone test for?

A solution of sodium iodide in acetone is a test for some alkyl chlorides and bromides. The mechanism is largely SN2, so primary alkyl halides react faster than secondary alkyl halides, and tertiary alkyl halides generally give no reaction.

Does sodium iodide react with acetone?

Sodium iodide is soluble in acetone while sodium chloride and sodium bromide are not. The reaction is driven toward products by mass action due to the precipitation of the poorly soluble NaCl or NaBr.

Is sodium iodide in acetone SN2?

For SN2 reactions, NaI in acetone is chosen as iodide ion is a good nucleophile and acetone is a polar aprotic solvent, favoring a SN2 mechanism.

Does NaI dissolve in acetone?

Here, Iodine anion is larger in size(ionic radius) than chlorine or bromine anion. This makes NaI attain some covalent properties. Therefore, it easily dissolves with dry acetone( which is an organic solvent and covalent character allows compunds to be soluble in Organic solvents).

What is acetone test?

Acetone, serum testing is used to assess acetone levels in the blood and confirm diseases such as ketonuria, metabolic acidosis, and malnutrition, which raise ketone body concentrations in the body.

What is the sodium iodide test?

The formation of a white precipitate indicates the presence of halides. When the sodium iodide solution is added to the unknown, a precipitate of sodium iodide might occur leading to a false positive test. Upon mixing, the precipitate of sodium iodide should dissolve.

Is alkyl iodide soluble in acetone?

Alkyl iodide is insoluble in acetone.

Why is sodium iodide used as a solution in acetone instead of water?

NaX (X = Cl, Br) is insoluble in acetone, but is soluble in water. So, if you have water/acetone system, the solubility of NaX is increased comparing to acetone. Solvation effect doesn’t have a big role on iodide ions and does not greatly impact it’s nucleophilicity.

Is sodium iodide in acetone a strong nucleophile?

To encourage an SN2 reaction mechanism you will use a solution of NaI in acetone. Iodide is a good nucleophile, and if it displaces bromide or chloride, NaBr or NaCl will precipitate (these are much less soluble in acetone than NaI).

Is acetone a nucleophile or electrophile?

Both the aldol and dehydration steps may be promoted by base or acid. A typical aldol condensation reaction, in which acetone enolate is the nucleophile and another molecule of acetone is the electrophile.

Does 2 Bromobutane react with sodium iodide in acetone?

R-2-Bromobutane is allowed to react with NaI in acetone.

Why is NaI more soluble than NaF?

5. The solubility trend of the sodium halide salts (NaF, NaCl, NaBr, NaI) is that the solubility increases with increasing ionic radius of the halide. This means the solubility increases down the halogen group when they are bonded to sodium ions. In other words, NaI is more soluble than NaBr.