What causes thrombocytopenia and leukopenia?
Low white blood cell count Conditions that can cause leukopenia include: autoimmune conditions such as lupus and HIV. bone marrow damage, such as from chemotherapy, radiation therapy, or exposure to toxins. bone marrow disorders.
Which drug causes thrombocytopenia and leukopenia?
Heparin, a blood thinner, is the most common cause of drug-induced immune thrombocytopenia. If a medicine prevents your bone marrow from making enough platelets, the condition is called drug-induced nonimmune thrombocytopenia.
What is anemia neutropenia and thrombocytopenia?
The premature destruction of red blood cells (hemolysis) is known as autoimmune hemolytic anemia or AIHA. Thrombocytopenia refers to low levels of platelets (idiopathic thrombocytopenia purpura or ITP in this instance). Neutropenia refers to low levels of certain white blood cells known as neutrophils.
Does myelofibrosis cause thrombocytopenia?
Myelofibrosis (MF) is a chronic myeloproliferative neoplasm characterized by bone marrow fibrosis, ineffective hematopoiesis, splenomegaly, constitutional symptoms, and shortened survival. Patients often experience multiple disease-associated, as well as treatment-emergent, cytopenias, including thrombocytopenia.
What drugs reduce platelet count?
The following are antiplatelet or anti-clotting drugs that reduce the platelet count: glycoprotein IIb/IIIa inhibitors, including abciximab, eptifibatide, and tirofiban. heparin….Over-the-counter (OTC) medications that can cause a low platelet count include:
- acetaminophen.
- ibuprofen.
- naproxen.
What does leukopenia mean?
Listen to pronunciation. (LOO-koh-PEE-nee-uh) A condition in which there is a lower-than-normal number of leukocytes (white blood cells) in the blood.
How do you treat myelofibrosis with thrombocytopenia?
Thrombocytopenia in MF has multiple causes including ineffective hematopoiesis, splenic sequestration, and treatment-related effects. Presently, allogeneic hematopoietic stem cell transplantation (HSCT) remains the only curable treatment for MF, which, unfortunately, is only a viable option for a minority of patients.