What is liposomal bupivacaine?

What is liposomal bupivacaine?

Liposomal bupivacaine (Exparel), manufactured by Pacira Pharmaceuticals, is a long-acting, local anesthetic FDA approved for single-dose infiltration into the surgical site to produce postsurgical analgesia.

How is bupivacaine liposome administered?

EXPAREL should be injected slowly (generally 1 to 2 mL per injection) with frequent aspiration to check for blood and minimize the risk of inadvertent intravascular injection.

Can you mix EXPAREL with bupivacaine?

Admixing with bupivacaine HCl Do not admix EXPAREL with any other agents prior to administration. Avoid additional use of anesthetics within 96 hours following administration of EXPAREL.

Does liposomal bupivacaine work?

In conclusion, liposomal bupivacaine is effective for treating postoperative pain when used via local infiltration when compared to placebo with a prolonged duration of action, predictable kinetics, and an acceptable side effect profile.

What is liposome injection?

Amphotericin B liposomal injection is used to treat fungal infections such as cryptococcal meningitis (a fungal infection of the lining of the spinal cord and brain) and visceral leishmaniasis (a parasitic disease that usually affects spleen, liver, and bone marrow) in certain people.

How do you administer bupivacaine?

Bupivacaine hydrochloride injection, USP contains Bupivacaine hydrochloride, an amide local anesthetic, as the active pharmaceutical ingredient. The route of administration for Bupivacaine Hydrochloride injection is by injection, for infiltration, perineural, caudal, epidural, or retrobulbar use.

What is the difference between lidocaine and bupivacaine?

Are Xylocaine and Marcaine the Same Thing? Xylocaine (lidocaine) and Marcaine (bupivacaine hydrochloride)are local anesthetics (numbing medicines used in one area). Marcaine is longer acting and used for a spinal block. Lidocaine is used for local or regional anesthesia.

Is bupivacaine the same as Marcaine?

Bupivacaine, marketed under the brand name Marcaine among others, is a medication used to decrease feeling in a specific area. In nerve blocks, it is injected around a nerve that supplies the area, or into the spinal canal’s epidural space.

What is DepoFoam?

DepoFoam technology consists of novel multivesicular liposomes characterized by their unique structure of multiple non-concentric aqueous chambers surrounded by a network of lipid membranes.