What is Isoflurophate used for?
Isoflurophate is used in the eye to treat certain types of glaucoma and other eye conditions, such as accommodative esotropia. They may also be used in the diagnosis of certain eye conditions, such as accommodative esotropia.
What type of enzyme inhibitor is DIPF diisopropyl Phosphorofluoridate?
Diisopropyl fluorophosphate is a parasympathomimetic drug irreversible anti-cholinesterase and has been used in ophthalmology as a miotic agent in treatment of chronic glaucoma, as a miotic in veterinary medicine, and as an experimental agent in neuroscience because of its acetylcholinesterase inhibitory properties and …
What drug inhibits acetylcholinesterase?
Acetylcholinesterase Inhibitors, Central
- Aricept ODT.
- donepezil transdermal.
- Exelon Patch.
Can DIPF inhibit trypsin?
The peptidases trypsin and chymotrypsin contain serine groups at the active site and are inhibited by DIFP.
What type of inhibitor is DIPF?
For example, nerve gases like diisopropyl fluorophosphate, DIPF, irreversibly inhibit nerve action by forming covalent bonds to the OH group of serine on the active site of the enzyme acetylcholinesterase. This inhibition increases both the level and duration of action of the neurotransmitter acetylcholine.
What does carbachol do to the body?
Carbachol is a potent, direct-acting parasympathomimetic agent with muscarinic effects. Clinically, constriction of the iris and ciliary body occur, with a subsequent decrease in intraocular pressure.
Is carbachol still used?
Carbachol is a quaternary ammonium compound that shares both the muscarinic and nicotinic actions of acetylcholine but is much more slowly deactivated. Carbachol has been used topically in ophthalmology and systemically (subcutaneously, for example in doses of 2 mg/day) for urinary retention.
What drugs inhibit AChE?
What do trypsin inhibitors do?
A trypsin inhibitor (TI) is a protein and a type of serine protease inhibitor (serpin) that reduces the biological activity of trypsin by controlling the activation and catalytic reactions of proteins.