What does hyperostosis frontalis interna do to you?
As hyperostosis frontalis interna is usually an incidental finding of no clinical significance patients are generally asymptomatic. Compression by calvarial thickening may lead to cerebral atrophy and may present with cognitive impairment, neuropsychiatric symptoms, headaches and epilepsy 1,3.
What causes thickening of the skull?
Mutations in the ANKH gene that cause autosomal dominant craniometaphyseal dysplasia impair the maturation (differentiation) of osteoclasts, which likely disrupts bone remodeling. Reduced breakdown of bone tissue can contribute to the bone thickening characteristic of craniometaphyseal dysplasia.
What is mild Hyperostosis?
Hyperostosis frontalis interna is a common, benign thickening of the inner side of the frontal bone of the skull. It is found predominantly in women after menopause and is usually asymptomatic.
Can you feel your frontal bone?
The side or lateral surface of the frontal bone forms one edge of the temporal fossa. This is an indentation in the skull behind the eye that you can easily feel.
Is hyperostosis frontalis interna?
Hyperostosis Frontalis Interna is characterized by the thickening of the frontal bone of the skull.
Can Hyperostosis Frontalis cause headaches?
Learning points. Hyperostosis frontalis interna (HFI) is a continuous overgrowth of the frontal bone and has been described in association with chronic headaches and rarely with seizures.
What are symptoms of DISH?
Symptoms
- Stiffness. Stiffness may be most noticeable in the morning.
- Pain. You might feel pain in your back or in other affected areas, such as your shoulder, elbow, knee or heel.
- Loss of range of motion. You might notice this most when stretching side to side.
- Difficulty swallowing or a hoarse voice.
What are the signs and symptoms of hyperostosis frontalis interna?
Increased serum alkaline phosphatase and elevated serum calcium may occur. The major feature of Hyperostosis Frontalis Interna is excessive growth or thickening of the frontal bone of the head.
What causes Morgagni-Stewart-Morel syndrome and hyperostosis frontalis interna?
The cause of Morgagni-Stewart-Morel syndrome and hyperostosis frontalis interna is unknown, although some have suggested that a hormonal imbalance due to genetic and environmental factors may be the cause of many of the symptoms of the syndrome. [3]
Is there a cure for hyperostosis frontalis interna?
As of now, there is no known cure for Hyperostosis Frontalis Interna. The treatment given for this condition is purely symptomatic. Strict diet for weight loss and controlling obesity is advised. Migraine headaches can be treated with preventive and abortive medications.
Which histologic findings are characteristic of Paget’s disease and endosteal osteoma?
If doubt persists, a histological evaluation is able to shed light on the case by describing thick lamellar bone deposition, predominantly on the inner table of the frontal bone. The pattern of bone deposition differs markedly when compared with patterns seen in Paget’s disease, endosteal osteoma, or osteosarcoma.