What does a positive anti-smooth muscle AB mean?

What does a positive anti-smooth muscle AB mean?

If your results show a high amount of SMA antibodies, it probably means you have the type 1 form of autoimmune hepatitis. A lower amount may mean you have the type 2 form of the disease.

What is the normal range for anti-smooth muscle antibody?

Titers generally range from 1:80-1:320 and persist for years. In viral hepatitis the titers are below 1:80 and are transient. Low titers (1:20 to 1:40) are found in approximately 50% of patients with primary biliary cirrhosis.

What does a smooth muscle antibody of 1/20 mean?

Smooth Muscle Antibody, IgG Titer Less than 1:20 Negative – No Antibody detected. 1:20-1:80 Weak Positive – Suggest repeat testing in two to three weeks with fresh specimen. 1:160 or greater Positive – Suggestive of autoimmune hepatitis or chronic active hepatitis. Interpretive Data: Refer to report.

Does autoimmune hepatitis go away?

Some people need to remain on treatment if they have relapsed many times or if their disease is severe. In some cases autoimmune hepatitis may go away without taking any medicines. But for most people, autoimmune hepatitis is a chronic disease. It can lead to scarring of the liver (cirrhosis).

How do you get autoimmune hepatitis?

Autoimmune hepatitis may develop after you’re infected with the measles, herpes simplex or Epstein-Barr virus. The disease is also linked to hepatitis A, B or C infection. Heredity. Evidence suggests that a predisposition to autoimmune hepatitis may run in families.

What is anti SM blood test?

Although anti-Smith (Sm) antibody is a highly specific antibody for systemic lupus erythematosus (SLE), the significance of anti-Sm antibody in patients with SLE is unclear. This study aimed to evaluate the association between anti-Sm antibodies and disease activity in patients with new-onset SLE.

Is autoimmune hepatitis painful?

Some of the most common symptoms may include: Extreme tiredness (fatigue) Yellowing of the skin and eyes (jaundice) Belly (abdominal) pain.

What is a smooth muscle antibody (SMA) test?

What is a smooth muscle antibody (SMA) test? This test looks for smooth muscle antibodies (SMAs) in the blood. A smooth muscle antibody (SMA) is a type of antibody known as an autoantibody. Normally, your immune system makes antibodies to attack foreign substances like viruses and bacteria.

What is anti–striated muscle (anti–Sm)?

Author: Abbas A Jowkar, MBBS; Chief Editor: Nicholas Lorenzo, MD, CPE, MHCM, FAAPL more… The anti–striated muscle (anti-SM) Ab refers to a class of antibodies against components of skeletal muscle including titin, the ryanodine receptor, myosin, and alpha-actin.

What is anti-smooth muscle antibody?

Anti-smooth muscle antibody is a blood test that detects the presence of antibodies against smooth muscle. The antibody is useful in making a diagnosis of autoimmune hepatitis. A blood sample is needed. This may be taken through a vein.

What does it mean if my SMA antibodies are high?

If your results show a high amount of SMA antibodies, it probably means you have the type 1 form of autoimmune hepatitis. A lower amount may mean you have the type 2 form of the disease. If no SMAs were found, it means your liver symptoms are being caused by something different than autoimmune hepatitis.