What clomipramine is used for?

What clomipramine is used for?

Clomipramine is used to treat obsessive compulsive disorder (OCD). OCD is a nervous condition wherein a person has recurring thoughts or ideas or does repetitive things because they are anxious. Clomipramine is a tricyclic antidepressant (TCA).

What are the most common side effects of clomipramine?

Dizziness, drowsiness, dry mouth, constipation, stomach upset, nausea, vomiting, changes in appetite/weight, flushing, sweating, tiredness and blurred vision may occur. Anxiety symptoms may temporarily worsen when you first start taking clomipramine.

What happens when you stop taking clomipramine?

Abstract. Abrupt or gradual discontinuation of tricyclic antidepressants may precipitate withdrawal symptoms. The most common of these are general somatic or gastrointestinal distress, anxiety and agitation, sleep disturbance, akathisia, parkinsonism, paradoxical behavioral activation and mania.

Does clomipramine help you sleep?

Clomipramine produced rapid changes in sleep with reduced sleep continuity and almost complete suppression of REM sleep as well as a redistribution of slow wave sleep. Delta waves during sleep were also found to be shifted to the earlier part of the night and increased in intensity.

Is clomipramine used for sleep?

Clomipramine is known to suppress REM sleep, and this property may be of value in treating certain features of narcolepsy. In a case reported here, clomipramine produced relief of cataplexy, sleep paralysis and hallucinations with considerable subjective improvement.

How do you know if clomipramine is working?

When will clomipramine start working? When used to treat OCD, clomipramine may need to be taken for 6 to 12 weeks before you notice an improvement in your symptoms. It may take 4 to 6 months to see the full effect of this medication.

Is clomipramine a strong antidepressant?

Clomipramine hydrochloride, a tricyclic antidepressant, is a potent inhibitor of serotonin reuptake and may affect dopaminergic neurotransmission, suppress rapid eye movement sleep, produce changes in electrocardiograms, and elevate plasma prolactin.

Is clomipramine a good antidepressant?

Clomipramine has an average rating of 7.0 out of 10 from a total of 36 ratings for the treatment of Depression. 67% of reviewers reported a positive effect, while 25% reported a negative effect.

Is clomipramine good for anxiety?

Clomipramine is used off-label to treat patients with depression, anxiety, treatment-resistant depression, cataplexy syndrome, insomnia, neuropathic pain, chronic pain, body dysmorphic disorder, panic disorder, premature ejaculation, pediatric nocturnal enuresis, and trichotillomania.

Does venlafaxine interact with clomipramine oral?

All generic drug interactions for venlafaxine oral (lists will include brand and generic names): clomipramine oral and venlafaxine oral. clomipramine oral and venlafaxine oral both increase causing a dangerous abnormal heart rhythm.

Can we measure clinical tolerance to venlafaxine?

We measured clinical tolerance (using the UKU Side Effect Rating Scale), blood pressure and heart rate, electrocardiogram (ECG), and blood TCA levels after adding venlafaxine IR.

Does clomipramine increase QTc interval?

clomipramine oral and venlafaxine oral both increase QTc interval. © 1994-2022 WebMD, LLC. Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider.