Is hypospadias a midline defect?
Hypospadias, a midline fusion defect of the male ventral urethra, is a relatively common genital anomaly occurring in 0.3 – 7 of 1000 live male births. The anatomical location of the misplaced urethral meatus determines the severity of this anomaly with the severity increasing from distal to proximal.
What is hypospadias with chordee?
Chordee is a birth defect in boys in which the penis is bent during an erection, which even infants can experience. Males with chordee often have hypospadias, a condition where the opening of the urethra tube through which urine passes is located on the underside of the penis rather than at the tip.
Is hypospadias and chordee the same?
They are not the same condition. But babies with hypospadias can sometimes have a curved penis, called chordee or congenital penile curvature.
Is hypospadias associated with other defects?
Hypospadias is the most common congenital anomaly affecting the genitals. Its association with other anomalies is rare. It has been reported that other malformations occur in 29.3% of the cases with hypospadias. The more proximal the meatus, the higher the risk for having another associated anomaly.
What is a midline defect?
A ventral or midline abnormality can be best described as a defect that occurs on the anterior (front) portion of a body, usually in the middle or center of the body. Numerous reports of ventral developmental defects (problems that occur before the baby is born) have been described in association with PHACE syndrome.
What is a chordee?
Chordee is a congenital condition (birth defect) resulting from abnormal development of the penis. In chordee, the penis usually curves downward. The urinary opening may be on the underside of the penis (hypospadias). Surgery can usually correct chordee.
Is chordee serious?
Chordee repair is generally very successful in childhood. If chordee is not diagnosed until adulthood, surgery can still be an effective treatment. Some men or older boys may require additional surgery to achieve a final repair of chordee.
Can chordee correct itself?
It is often found when parents bring their children to the doctor due to a bend in the penis. Often, chordee alone is caused by skin tethering. Most of the time, this can be easily corrected.
Is hypospadias linked to autism?
The common psychiatric disorders in hypospadias patients were attention-deficit hyperactivity, autism spectrum, and behavioral/emotional disorders. A previous study showed that boys aged 6–10 years with hypospadias had anxiety than the controls (33).
Are midline defects genetic?
Opitz syndrome (OS) is an inherited disorder characterized by midline defects including hypertelorism, hypospadias, lip-palate-laryngotracheal clefts and imperforate anus.
Does everyone have MTHFR gene?
Everyone has two MTHFR genes, one inherited from your mother and one from your father. Mutations can occur in one or both MTHFR genes. There are different types of MTHFR mutations. An MTHFR test looks for two of these mutations, also known as variants.
How do you know if your baby has chordee?
The most visible symptom of chordee is a sharp curve of the penis, either upward or downward. This curve can start anywhere from the base of the penis near the testicles to the beginning of the glans. If you also have hypospadias, your urine may splash or go in an unintended direction when you urinate.