How much does Epicel cost?
The second reason is cost, which, for EpicelTM, is estimated to be as much as $13,000 per 1% of body surface treated (Rue, Cioffi et al.
What is an Epicel?
Epicel is a type of graft made from a patient’s own skin. It is also called “Cultured Epidermal Autograft” or “CEA.” These grafts provide a permanent skin replacement for patients with deep dermal or full thickness burns.
What is an epidermal autograft?
Cultured Epidermal Autograft: a tissue grown from one’s own skin cells for use in placing on the person’s own body.
What is biobrane made of?
Biobrane® (a type of artificial skin) is a man made skin substitute composed of nylon mesh, silicone and collagen (derived from pig skin). It is a stretchable dressing that is used as a temporary cover for clean partial thickness burns and donor sites or as a protective covering over meshed skin grafts.
Is Epicel FDA approved?
1998: FDA designated Epicel as a combination product and as a Humanitarian Use Device (HUD). 2007: FDA’s Center for Devices and Radiologic Health (CDRH) approved Epicel under the HDE regulatory statute.
Can foreskin be used for skin grafts?
The prepuce, or foreskin, has been used as a skin graft for a number of indications.
Is biobrane a skin substitute?
Is dermagraft a skin substitute?
Dermagraft is a sterile, cryopreserved, human fibroblast–derived dermal substitute generated by the culture of neonatal dermal fibroblasts onto a bioresorbable polyglactin mesh scaffold (Fig. 1).
Is Skin grafting major surgery?
Skin grafting involves removing damaged or dead skin tissue and replacing it with new, healthy skin. Skin grafting is major surgery with serious risks and potential complications. You may have less invasive treatment options.
Interestingly, Epicel is a treatment for deep dermal or full thickness burns comprising a total body surface area of greater than or equal to 30%. It has higher pricing of $6,000-10,000 per 1% of total body surface area, because it is not used to treat a single wound site, but rather used to treat a large surface area of the patient’s body.
When did Genzyme biosurgery stop supplying Epicel?
From 1988 to 1996, Genzyme Biosurgery had supplied Epicel for the treatment of approximately 1300 patients with burn injuries. The product had been considered a banked human tissue until 1996 when FDA announced that manipulated
What is Epicel used for?
Epicel (cultured epidermal autografts) is authorized for use in adults and pediatric patients who have deep dermal or full thickness burns comprising a total body surface area greater than or equal to 30%.
What are Epicel grafts?
These grafts provide a permanent skin replacement for patients with deep dermal or full thickness burns. Epicel is the only treatment of this type approved by the Food and Drug Administration (FDA) for use in the United States. Epicel grafts are made by growing a patient’s own skin cells in an incubator.