What is the genome of reovirus?
Viruses in the family Reoviridae have genomes consisting of segmented, double-stranded RNA (dsRNA). Because of this, replication occurs exclusively in the cytoplasm, and the virus encodes several proteins which are needed for replication and conversion of the dsRNA genome into positive-sense RNAs.
Is reovirus DNA or RNA?
Reovirus is a nonenveloped double-stranded RNA virus. This virus was initially not known to be related to any specific disease, and so was named Respiratory Enteric Orphan virus. However, some members of the reovirus family have been shown to cause mild illnesses such as diarrhea [5,30].
How many ds DNA segments are present in the reovirus genome?
The Reoviridae represents the largest family of dsRNA viruses. It contains 15 genera of viruses having genomes composed of 9, 10, 11 or 12 segments of linear dsRNA.
How many dsRNA segments are present in the reovirus genome * 1 point?
Like other members of the family, the reoviruses are non-enveloped and characterized by concentric capsid shells that encapsidate a segmented dsRNA genome. In particular, reovirus has eight structural proteins and ten segments of dsRNA.
What is reovirus in poultry?
Avian reoviruses (ARVs) are double-stranded RNA viruses, belonging to the Reoviridae family in the genus Orthoreovirus, and causing arthritis and tenosynovitis in broilers, broiler breeders and turkeys (TARV). Avian reoviruses are present all over the world and antibodies can be found in various types of birds.
What causes human reovirus?
Human volunteer studies have failed to demonstrate a clear cause-and-effect relationship between reoviruses and human illness. The method of transmission of reoviruses is unknown. However, because these viruses are recovered most frequently from the feces, primary spread seems most likely to be by the fecal-oral route.
How many mammalian reovirus proteins are involved in the control of the interferon response?
In addition, although three reovirus proteins harbor an immunoreceptor tyrosine-based activation (ITAM) motif, only that of μ2 (YXXLX9YXXL) is actually functional and appears responsible for NF-kB activation, which could result in interferon induction in some cell types [78].
How is reovirus transmitted?
The method of transmission of reoviruses is unknown. However, because these viruses are recovered most frequently from the feces, primary spread seems most likely to be by the fecal-oral route.