What is drug induced encephalopathy?
Abstract. The clinical features of an antiepileptic drug-induced encephalopathy (ADE) are confusion, reduction of vigilance, neurological deficits or an increase of the seizure frequency. In the electroencephalogram a general slowing or epileptic discharges are found.
What drugs cause toxic encephalopathy?
Many drugs may cause toxic encephalopathy….Toxic encephalopathy.
| Type of therapeutic agent | Drugs |
|---|---|
| Antineoplastic agents | Methotrexate (± seizures, leukotoxic damage) |
| Ifosfamide | |
| Paclitaxel (± seizures) | |
| Cisplatin (± seizures, leukotoxic damage) |
What can cause encephalopathy?
The causes of encephalopathy are numerous and varied; they include infections, anoxia, metabolic problems, toxins, drugs, physiologic changes, trauma, and other causes. Encephalopathy is a general term that means brain disease, damage, or malfunction. The major symptom of encephalopathy is an altered mental state.
Can you recover from toxic encephalopathy?
The treatment of diffuse acute encephalopathy is primarily supportive, starting with removal of the exposure source. For most of the neurotoxins that act diffusely on the brain, recovery from acute exposure is complete [4].
What are symptoms of neurotoxicity?
Symptoms of neurotoxicity include memory and concentration problems; confusion; multiple sclerosis or MS-type symptoms; impaired control of the limbs, bladder, or bowels; headaches or migraines; sleep disorders, including sleep apnea; eye problems that are neurological in origin; balance and hearing problems; muscle …
Does encephalopathy go away?
In reversible encephalopathy, such as from organ failure, metabolic conditions, or infections, symptoms usually go away when you fix the problem that’s causing them, and you may be able to regain your previous mental abilities.
How do you fix encephalopathy?
The treatment for encephalopathy varies depending on what caused it. Treatment may include medications to treat your symptoms and medications or surgery to treat the underlying cause. Your doctor may recommend nutritional supplements to slow the damage to your brain, or a special diet to treat underlying causes.
Can encephalopathy go away on its own?
Does encephalopathy show on MRI?
MRI is the imaging modality of choice and is often the first indicator of an encephalopathy as a possible cause of symptoms.