What factor is deficient in Christmas disease?
Hemophilia B, also called factor IX (FIX) deficiency or Christmas disease, is a genetic disorder caused by missing or defective factor IX, a clotting protein. Although it is passed down from parents to children, about 1/3 of cases are caused by a spontaneous mutation, a change in a gene.
What is Christmas syndrome?
Christmas disease, also called hemophilia B or factor IX hemophilia, is a rare genetic disorder in which your blood doesn’t clot properly. If you have Christmas disease, your body produces little or no factor IX. This leads to prolonged or spontaneous bleeding.
Which factor is decreased in Christmas hemophilia?
This is also referred to as classic hemophilia or factor VIII deficiency. Hemophilia B. This is caused by a deficiency of factor IX. This is also called Christmas disease or factor IX deficiency.
Why is Factor 9 deficiency called Christmas disease?
Hemophilia B occurs when clotting factor IX is either absent or not present in sufficient amounts. Hemophilia B is also known as Christmas disease. It is named after the first person to be diagnosed with the disorder in 1952, Stephen Christmas.
Which factor is Christmas factor?
Hemophilia B is the second most common type of hemophilia. It is also known as factor IX deficiency, or Christmas disease. It was originally named “Christmas disease” after the first person diagnosed with the disorder back in 1952.
Which of the following factor is known as Christmas factor?
The clotting factor IX is also known as Christmas factor. The name is derived from the boy, Stephen Christmas. He was lacking this factor and the deficiency led him to acquire hemophilia.
What are the symptoms of hemophilia B?
Symptoms
- Bleeding into joints with associated pain and swelling.
- Blood in the urine or stool.
- Bruising.
- Gastrointestinal tract and urinary tract bleeding.
- Nosebleeds.
- Prolonged bleeding from cuts, tooth extraction, and surgery.
- Bleeding that starts without cause.
What mutation causes Christmas disease?
Hemophilia B is a genetic disorder caused by missing or defective factor IX, a blood-clotting protein also known as FIX. The disorder also is known as Christmas Disease, after the first person to be diagnosed with this type: Stephen Christmas, in 1952. It is the second most common type of hemophilia.
How is Factor 9 deficiency Treated?
Standard treatment is infusion of factor IX concentrates to replace the defective clotting factor. The amount infused depends upon the severity of bleeding, the site of the bleeding, and the size of the patient.