What does DCIS with necrosis mean?

What does DCIS with necrosis mean?

High-grade DCIS may be described as comedo or comedo necrosis, which means there are areas of dead cancer cells inside the DCIS.

Is carcinoma in situ high grade?

DCIS that is high grade, is nuclear grade 3, or has a high mitotic rate is more likely to come back (recur) after it is removed with surgery. DCIS that is low grade, is nuclear grade 1, or has a low mitotic rate is less likely to come back after surgery.

What happens if DCIS is not treated?

The cells in DCIS are cancer cells. If left untreated, they may spread out of the milk duct into the breast tissue. If this happens, DCIS has become invasive (or infiltrating) cancer, which in turn can spread to lymph nodes or to other parts of the body.

What are the chances of getting DCIS in the other breast?

Breast cancer may develop in the patient’s other breast, but only in about 5% of cases. If this happens, the cancer in the second breast is not considered a recurrence, but a new primary breast cancer.

What is lobular carcinoma in situ?

Lobular carcinoma in situ (LCIS) is an uncommon condition in which abnormal cells form in the milk glands (lobules) in the breast. LCIS isn’t cancer. But being diagnosed with LCIS indicates that you have an increased risk of developing breast cancer.

How is lobular carcinoma in situ (LCIS) treated?

Surgery to remove the area of LCIS and a small margin of healthy tissue that surrounds it may be recommended in certain situations. For instance, a specific type of LCIS called pleomorphic lobular carcinoma in situ (PLCIS) is thought to carry a greater risk of breast cancer than the more common classical type.

What does in-situ carcinoma with duct and lobular features mean?

In-situ carcinoma with duct and lobular features means that the in-situ carcinoma looks like DCIS in some ways and LCIS in some ways (when seen under the microscope), so the pathologist can’t call it one or the other. Lobular carcinoma in situ (LCIS) is a type of in-situ carcinoma of the breast.

What is the difference between LCIS with necrosis and without necrosis?

Necrosis means that some of the LCIS cells are dead. LCIS with either of these features (when compared to LCIS without them) may be more likely to grow faster and to spread, and is linked to an even higher risk of invasive cancer. LCIS with either of these features may be treated differently than most cases of LCIS.