What are the complications of situs inversus?

What are the complications of situs inversus?

Because the organs can be functional in situs inversus, it’s possible for a person to have no complications. Other patients can experience cardiac dysfunction or a lung condition called primary ciliary dyskinesia (PCD), which causes mucus buildup in the lungs. This can lead to chronic bronchitis and sinusitis.

Can you have dextrocardia and situs inversus?

Some people have dextrocardia with situs inversus as part of an underlying condition called primary ciliary dyskinesia. Primary ciliary dyskinesia can result from changes ( mutations ) in several different genes, including the DNAI1 and DNAH5 gene; however, the genetic cause is unknown in many families.

What causes dextrocardia situs inversus?

Causes. Dextrocardia with Situs Inversus, a rare condition that is present at birth, is transmitted by autosomal recessive genes. The primitive loop in the embryo moves into the reverse direction of its normal position during fetal development, causing displacement of organs.

How rare is dextrocardia situs inversus totalis?

As it is recessive genes that cause dextrocardia, an individual must inherit a copy of the abnormal gene from both parents to develop the condition. Dextrocardia affects an estimated 1 out of every 12,000 people . Dextrocardia situs inversus totalis affects approximately 1 out of every 10,000 children.

Can you get pregnant with situs inversus?

There were 6 pregnancies in 3 patients with situs inversus and 9 pregnancies in 6 patients with isolated dextrocardia. There were no apparent antenatal complications. None of the patients developed any cardiac symptoms antenatally.

How is dextrocardia diagnosed?

Isolated dextrocardia usually causes no symptoms. The condition is usually found when an X-ray or an MRI of your chest shows the location of your heart on the right side of your chest. Some people with isolated dextrocardia have an increased risk of lung infections, sinus infections, or pneumonia.

How rare is situs inversus dextrocardia?

Dextrocardia is a very rare condition, and studies have revealed incidence rates of dextrocardia to be around 1 in 12000 pregnancies. [7] Kartagener syndrome has an incidence rate of about 1 in 30,000 live births, and situs inversus totalis was seen in around 50% of patients with primary ciliary dyskinesia.

Can you have a baby with situs inversus?

Situs inversus with pregnancy is a rare clinical entity. However, these patients are likely to have uneventful course during pregnancy.

Does situs inversus affect the brain?

Yet individuals with anatomical reversals in brain structure, due to a condition called situs inversus totalis, still retain left-sided language processing [4]. These results suggest that, for some cognitive tasks, function may not follow structure.