Can muscular dystrophy cause depression?
The physical and social hardships associated with the disease often lead to psychological stress disorders such as depression and anxiety, in muscular dystrophy patients. Psychological stress affects both mental and physical health.
Does myotonic dystrophy affect the brain?
It is now accepted that Myotonic Dystrophy can directly affect the brain. There are well described changes in structure which are visible on scans.
What does myotonic dystrophy affect?
Myotonic muscular dystrophy is a common multi-system disorder that affects the skeletal muscles (the muscles that move the limbs and trunk) as well as smooth muscles (the muscles that control the digestive system) and cardiac muscles of the heart.
What causes Steinert disease?
Type 1 DM (DM1), long known as Steinert disease, occurs when a gene on chromosome 19 called DMPK contains an abnormally expanded section located close to the regulation region of another gene, SIX5.
How does muscular dystrophy affect emotional development?
In children affected with DMD were also observed affective disorders, depressive issues and hypochondriac fears. In many dystrophic patients was noted that, beyond a certain stage of disease, appeared significant psychological and psychopathological problems in the boy and in the household.
How does muscular dystrophy affect mental health?
This research, recently published in the Journal of Developmental and Behavioral Pediatrics, found that nearly half (45%) of the oldest males in each family affected with DBMD had at least one of three mental health concerns: behavior concerns, depressed mood, or attention-deficit/hyperactivity disorder (ADHD).
What triggers myotonic dystrophy?
Myotonic dystrophy Type 1 is caused by a mutation in the DMPK gene. Type 2 myotonic dystrophy is caused by a mutation in the CNBP gene. Mutations in each of these genes involve a short segment of DNA that is abnormally repeated many times. This abnormal repetition forms an unstable region of the gene.
How is Steinert disease diagnosed?
Diagnosis is confirmed by the demonstration of an abnormality at the 19q13-2 locus, with the use of molecular genetic techniques. Its transmission is autosomal dominant, and anticipation may occur, that is, disease may be more severe and occur earlier in offspring.
What are the symptoms of muscular dystrophy in adults?
General Muscular Dystrophy Symptoms
- Muscle weakness.
- Difficulty walking.
- Frequent falling.
- Difficulty getting up from a lying or sitting position.
- Limited movement at certain joints (called contracture)
- Heart problems.
- Problems with breathing and swallowing.
- Muscle pain or stiffness.
Does muscular dystrophy affect your mind?
The molecular missteps that disrupt brain function in the most common form of adult-onset muscular dystrophy have been revealed in a new study. Myotonic dystrophy is marked by progressive muscle wasting and weakness, as well as sleepiness, memory problems, and mental retardation.