What is besylate salt?
Description. Amlodipine benzenesulfonate is the benzenesulfonate salt of amlodipine. It has a role as a vasodilator agent, a calcium channel blocker and an antihypertensive agent. It contains an amlodipine. ChEBI.
What is besylate used for?
Amlodipine Besylate is used in adults and children six years or older to treat chest pain and other conditions caused by coronary artery disease. Amlodipine Besylate is also used to treat high blood pressure (hypertension).
What salt is in amlodipine?
Background: The commercially available formulation of amlodipine is conjugated with besylate salt to increase water solubility. Recently, a new amlodipine salt formulation has been developed in which the free base of amlodipine is conjugated with a chemically different salt, adipate.
What is the difference between maleate and besylate?
Amlodipine, marketed primarily as a besylate salt, is a calcium channel blocker used for treating essential hypertension. Amlodipine maleate is another salt that is considered, in terms of pharmacokinetics and pharmacodynamics, similar to amlodipine besylate.
What is the difference between Norvasc and amlodipine besylate?
NORVASC is the besylate salt of amlodipine, a long-acting calcium channel blocker. Amlodipine besylate is a white crystalline powder with a molecular weight of 567.1.
What is the difference between amlodipine besylate and amlodipine benazepril?
Amlodipine is a calcium channel blocker. Amlodipine relaxes (widens) blood vessels and improves blood flow. Benazepril is an ACE inhibitor. ACE stands for angiotensin converting enzyme.
What are the side effects amlodipine besylate?
Amlodipine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
- swelling of the hands, feet, ankles, or lower legs.
- headache.
- upset stomach.
- nausea.
- stomach pain.
- dizziness or lightheadedness.
- drowsiness.
- excessive tiredness.