What causes subacute sclerosing panencephalitis?
Subacute sclerosing panencephalitis is thought to be caused by a slow measles virus (paramyxovirus). Slow viruses may stay dormant in humans for extended periods of time, then for reasons yet unknown may become reactivated.
What is the meaning of Panencephalitis?
[ păn′ĕn-sĕf′ə-lī′tĭs ] n. Encephalitis that affects both the gray and white matter of the brain, resulting in progressive loss of mental and motor functions.
Is subacute sclerosing panencephalitis a latent disease?
Subacute sclerosing panencephalitis (SSPE)—also known as Dawson disease—is a rare form of chronic, progressive brain inflammation caused by slow infection with certain defective strains of hypermutated measles virus….
| Subacute sclerosing panencephalitis | |
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| Subacute sclerosing panencephalitis. | |
| Specialty | Infectious diseases |
How does measles cause subacute sclerosing panencephalitis?
Measles virus may cause immediate symptoms of brain infection (encephalitis. The spinal cord may also be involved… read more ), or the virus may remain in the brain for a long time without causing problems. Subacute sclerosing panencephalitis occurs because the measles virus reactivates.
How common is subacute sclerosing panencephalitis?
Subacute sclerosing panencephalitis occurs because the measles virus reactivates. In the past in the United States, for reasons that are not known, the disorder occurred in about 7 to 300 people per million people who had measles infection and in about 1 person per million people who received the measles vaccine.
Which disease has a very rare side effect called subacute sclerosing panencephalitis?
An abnormal reaction by your immune system to the measles virus, or rubeola, is likely the cause. It causes inflammation, swelling, and irritation of your brain. It may occur years after you recover from the measles. SSPE is a rare disease.
What disorders can be caused by measles encephalitis?
About 1 child out of every 1,000 who get measles will develop encephalitis (swelling of the brain) that can lead to convulsions and can leave the child deaf or with intellectual disability. Death.
What group of viruses does measles belong to?
Pathogen name and classification Measles is caused by Rubeola virus, which belongs to the Paramyxovirus family. Measles is an acute systemic viral infection with fever, respiratory involvement and symptoms, and a rash.
How common is SSPE after measles?
PIP: The incidence of subacute sclerosing panencephalitis (SSPE), a progressive and fatal neurodegenerative disease caused by the measles virus, has declined with widespread use of measles vaccine. The risk of SSPE after measles vaccination has been estimated at 0.7/million doses.
What is rubella IgG and IgM?
When the body is infected with the rubella virus, it defends itself by producing two types of antibodies in sequence: first, IgM, which appears 3 to 7 days after the onset of symptoms and is present for a few weeks, then IgG, which appears a few days after IgM and lasts for the rest of that person’s life.
What is subacute sclerosing panencephalitis (SSPE)?
Subacute sclerosing panencephalitis (SSPE) is a progressive neurological disorder of children and young adults that affects the central nervous system (CNS). It is a slow, but persistent, viral infection caused by defective measles virus.
What is SSPE in medical terms?
View Full Treatment Information. Definition. Subacute sclerosing panencephalitis (SSPE) is a progressive neurological disorder of children and young adults that affects the central nervous system (CNS). It is a slow, but persistent, viral infection caused by defective measles virus.
What is the best treatment for sclerosing panencephalitis?
Good nursing care is the most important aspect of treatment for SSPE, along with anticonvulsant and antispasmodic drugs when needed. Subacute sclerosing panencephalitis (SSPE) is a progressive neurological disorder of children and young adults that affects the central nervous system (CNS).