What causes Kashin Beck disease?
The aetiology of Kashin-Beck disease (KBD) remains elusive. Four factors have been convincingly associated with the disease: selenium deficiency, iodine deficiency, grain contamination with mycotoxin-producing fungi, and water pollution with organic material and fulvic acid.
Is there selenium in fulvic acid?
A diet containing sodium selenite and fulvic acid caused the selenium concentrations in the organs, with the exception of the spleen, to be lower than observed with the selenite-only diet.
What causes Keshan disease?
Keshan disease is a congestive cardiomyopathy caused by a combination of dietary deficiency of selenium and the presence of a mutated strain of Coxsackievirus, named after Keshan County of Heilongjiang province, Northeast China, where symptoms were first noted.
What is Keshan’s disease?
Keshan disease is a reversible endemic cardiomyopathy, characterized by focal myocardial necrosis associated with inflammatory infiltrates and calcification, which can lead to acute or chronic episodes of cardiogenic shock and congestive heart failure [32].
What is Kashin?
Kashin Beck Disease (KBD) is a chronic joint disease with decreased health conditions causing major functional limitations and disability of unknown origin. KBD has a typical crescent geographical distribution, primarily in agricultural regions of eastern Siberia, northern Korea and in the central regions of China.
What is one symptom of selenium toxicity?
Selenium toxicity can occur with acute or chronic ingestion of excess selenium. Symptoms of selenium toxicity include nausea; vomiting; nail discoloration, brittleness, and loss; hair loss; fatigue; irritability; and foul breath odor (often described as “garlic breath”). Selenium is found in the environment in soil.
What foods are high in selenium?
Selenium and Healthful Diets
- Many whole grains and dairy products, including milk and yogurt, are good sources of selenium.
- Pork, beef, turkey, chicken, fish, shellfish, and eggs contain high amounts of selenium.