What are atypical glands?
Abstract. Atypical glands suspicious but not diagnostic of carcinoma indicate that the pathologic findings are not sufficient for a definitive diagnosis of cancer but suspicious enough for further investigation. Therefore, a rebiopsy should be recommended.
What does Atypical Pathology mean?
Atypical is a word pathologists use to describe cells that look abnormal either in shape, colour, or size compared to normal, healthy cells in the same location. Pathologists may also describe these changes as cytologic atypia.
Is atypical small acinar proliferation cancer?
Abstract. Atypical small acinar proliferation is a histopathological diagnosis of unspecified importance in prostate needle-biopsy reports, suggestive but not definitive for cancer.
What is atypical proliferation?
Atypical small acinar proliferation (ASAP) that is suspicious for malignancy is not a specific pathologic entity; instead, it is a diagnosis that incorporates a continuum ranging from benign, histologically atypical mimics of cancer to marginally sampled cancer.
What does atypical mean in medical terms?
abnormal
Atypical (ay-TIP-ih-cul) is a medical word for “abnormal.” Doctors may use this word to describe cells or body tissues that look unusual under a microscope. They might also say your case is atypical if you don’t have the usual symptoms of your type of cancer.
What is ASAP on prostate biopsy?
ASAP stands for atypical small acinar proliferation. ASAP isn’t a medical condition but is a term used to describe changes to prostate cells seen under the microscope, when it isn’t clear whether the cells are cancer. For example, there may not be enough changed cells for the doctor to say whether they are cancer.
Should I be worried about atypical cells?
Atypical cells don’t necessarily mean you have cancer. However, it’s still important to make sure there’s no cancer present or that a cancer isn’t just starting to develop. If your doctor identifies atypical cells, close follow-up is essential.
What is ASAP in prostate cancer?
Atypical small acinar proliferation (ASAP) occurs in approximately 5% of prostate biopsies. Approximately 30–40% of patients with ASAP have biopsy detectable prostate cancer (PCa) within 5 years. Current guidelines recommend a repeat biopsy within 3–6 months after the initial diagnosis.
What is precancerous prostate?
Precancerous conditions of the prostate are those that have the potential to cause cancer. Precancerous tissues contain cells with abnormalities that have arisen from DNA mutation. Sometimes, these abnormal cells proliferate and cancer develops.
What does a Gleason score of 7 mean?
Gleason scores of 5 or lower are not used. The lowest Gleason score is 6, which is a low-grade cancer. A Gleason score of 7 is a medium-grade cancer, and a score of 8, 9, or 10 is a high-grade cancer. A lower-grade cancer grows more slowly and is less likely to spread than a high-grade cancer.