Which anti hypertensive medication is more effective in African-Americans?
Experts recommend Black adults start with either a thiazide diuretic — such as chlorthalidone or hydrochlorothiazide — or a calcium channel blocker like amlodipine (Norvasc).
What ethnic variations in drug response are associated with antihypertensive medications explain?
The most convincing evidence at that time came from a VA Cooperative Trial,1 which along with other smaller studies, suggested that whites (those of European ancestry) had a better antihypertensive response to β-blockers than blacks (those of African ancestry), while blacks had a slight better response to diuretics …
What blood pressure medication should African-Americans not take?
Angiotensin converting enzyme (ACE) inhibitors have been avoided as an initial therapeutic option in the treatment of hypertension in African-Americans. A major reason for this has been the widespread perception of clinicians that these agents have poor blood pressure (BP) lowering efficacy in this population.
Does ethnicity affect hypertension?
The prevalence of high blood pressure differs by race/ethnicity, with the condition being more common among blacks (40.4%) compared with whites (27.4%) and Mexican-Americans (26.1%).
What drug classes should be considered first in the African American population for hypertension?
In the text of the guideline, mentions that diuretics should be the agent of first choice for blacks with hypertension because of their proven effectiveness in clinical trials. For whites, beta-blockers are also an option for first line therapy. Mono-therapy with beta-blockers or ACE-Is is less effective in blacks.
Which ethnicity is more prone to hypertension?
Among normal/underweight people, non-Hispanic black (AOR, 6.6; 95% CI, 2.7–16.0) and Asian adults (AOR, 5.8; 95% CI, 2.3–14.9) had approximately 6 times greater odds of hypertension than white adults, whereas Hispanics had 3.5 (95% CI, 1.4–8.7) times greater odds of hypertension than white adults.