What is the mechanism of action of asenapine?
Mechanism of Action Saphris (asenapine) is a sublingual psychotropic agent. The exact mechanism of action is unknown. However, it has been suggested that the efficacy of asenapine in schizophrenia is mediated through a combination of antagonist activity at D2 and 5-HT2A receptors.
What class of drug is Saphris?
Asenapine is a psychiatric medication that belongs to the class of drugs called atypical antipsychotics. It works by helping to restore the balance of certain natural substances in the brain (neurotransmitters).
What is cariprazine used for?
Cariprazine is a medication that works in the brain to treat schizophrenia. It is also known as a second-generation antipsychotic (SGA) or atypical antipsychotic. Cariprazine rebalances dopamine and serotonin to improve thinking, mood, and behavior.
Is Saphris anticholinergic?
It has moderate affinity for histamine H2 receptors and somewhat higher affinity for histamine H1 receptors but no appreciable affinity for muscarinic cholinergic M1 receptors. 1 Therefore, asenapine would be expected to have strong serotonergic, dopaminergic, and adrenergic effects but no anticholinergic effects.
What kind of drug is asenapine?
Asenapine is in a class of medications called atypical antipsychotics. It works by changing the activity of certain natural substances in the brain.
What is the brand name for asenapine?
Asenapine
| Clinical data | |
|---|---|
| Trade names | Saphris, Sycrest, Secuado |
| Other names | ORG-5222 |
| AHFS/Drugs.com | Monograph |
| MedlinePlus | a610015 |
Is SAPHRIS a mood stabilizer?
Asenapine is a medication that works in the brain to treat schizophrenia. It is also known as a second generation antipsychotic (SGA) or atypical antipsychotic. Asenapine rebalances dopamine and serotonin to improve thinking, mood, and behavior.
What class of drugs is cariprazine?
Cariprazine is in a class of medications called atypical antipsychotics. It works by changing the activity of certain natural substances in the brain.
What are the side effects of cariprazine?
Side Effects
- Blurred vision.
- dizziness.
- drooling.
- inability to move the eyes.
- inability to sit still.
- increased blinking or spasms of the eyelid.
- loss of balance control.
- muscle trembling, jerking, or stiffness.
Is Saphris an atypical antipsychotic?
Saphris (asenapine) is an atypical antipsychotic psychiatric medication used to treat certain mental/mood disorders (such as schizophrenia, bipolar disorder).
Is Saphris like Zyprexa?
Zyprexa (olanzapine) is good for treating psychosis, mania, and agitation, but it’s more likely to cause weight gain and sleepiness than other antipsychotics. Saphris (asenapine) can be used to treat bipolar disorder in children age 10 or older, and schizophrenia in children age 12 or older.