What is tamoxifen used for?

What is tamoxifen used for?

What is tamoxifen? Tamoxifen blocks the actions of estrogen, a female hormone. Certain types of breast cancer require estrogen to grow. Tamoxifen is used to treat some types of breast cancer in men and women. It is also used to lower a woman’s chance of developing breast cancer if she has a high risk (such as a family history of breast cancer).

Does tamoxifen work better on low dose?

Lower-Dose Tamoxifen Works As Well As High-Dose. Now, new research shows that a lower dose of the hormone therapy helped prevent breast cancer from returning and guarded against new cancers in women who had high-risk breast tissue. On top of that, the lower dose — just 5 milligrams daily — came with fewer troubling side effects. “Low-dose…

What are the different brands of tamoxifen?

Here are the two formulations of the different brands. Brand Relonchem: tamoxifen 20mg, calcium hydrogen phosphate, microcrystalline cellulose, sodium starch glycolate, povidone, magnesium stearate and colloidal anhydrous silica. Brand Chelonia: tamoxifen 20mg, calcium hydrogen phosphate, povidone k25, sodium starch glycolate,…

Can tamoxifen cause breast cancer?

They all had either stage 0 breast cancer (called DCIS) or high-risk lesions in their breast tissue that could develop into breast cancer. Half of the women took 5 milligrams of tamoxifen daily for three years.

Tamoxifen is used to treat breast cancer that has spread to other parts of the body in men and women. It is used to treat early breast cancer in women who have already been treated with surgery, radiation, and/or chemotherapy.

What is anastrozole used for?

Anastrozole is used to treat early hormone receptor-positive breast cancer. It is also used for first-line treatment of hormone receptor-positive or hormone receptor-unknown advanced or metastatic (cancer that has spread) breast cancer.

What are the most common side effects of tamoxifen?

What are the side effects of taking tamoxifen?

• Menopause-like symptoms, including hot flashes, night sweats and vaginal dryness.
• Weight gain (more common) or fluid retention (edema).
• Irregular or loss of menstrual periods.
• Leg swelling.
• Nausea.
• Vaginal discharge.
• Skin rash.
• Erectile dysfunction .

How does tamoxifen work in treating breast cancer?

Tamoxifen blocks estrogen from connecting to the cancer cells and telling them to grow and divide. While tamoxifen acts like an anti-estrogen in breast cells, it acts like an estrogen in other tissues, like the uterus and the bones. Because of this, it is called a selective estrogen receptor modulator (SERM).

How do you take tamoxifen liquid?

Take this medication by mouth with or without food, usually once or twice daily for 5 years, or as directed by your doctor. Daily dosages greater than 20 milligrams are usually divided in half and taken twice a day, in the morning and evening, or as directed by your doctor.

Is tamoxifen liver toxic?

Hepatotoxicity. Tamoxifen has been associated with rare instances of idiosyncratic, clinically apparent liver injury, typically arising within the first six months of treatment and having variable presentations with cholestatic, mixed or hepatocellular pattern of enzyme elevations.

Does anastrozole weaken your immune system?

Taking hormone therapy, including tamoxifen, letrozole, anastrozole, exemestane and goserelin, does not affect your immune system. Hormone therapies do not increase your risk of getting coronavirus or of becoming seriously ill if you do get it.

What are the major side effects of anastrozole?

Anastrozole may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

• weakness.
• headache.
• hot flashes.
• sweating.
• stomach pain.
• nausea.
• vomiting.
• loss of appetite.

Can tamoxifen make you smell?

Some women may also experience abnormal discharge. This can be a change in amount, appearance or smell of discharge.

What foods should not be eaten when taking tamoxifen?

The foods of most concern for women taking tamoxifen are grapefruit and tangerines. Grapefruit is well-known to interfere with numerous medications. Many drug-interaction resources specifically advise that women taking tamoxifen avoid grapefruit.

Can breast cancer come back while on tamoxifen?

While tamoxifen can lower the chance of hormone receptor-positive breast cancer coming back (as well as the risk of getting a second breast cancer), it can increase the risk of uterine cancer (endometrial cancer and uterine sarcoma).

Does tamoxifen weaken the immune system?

What is in soltamox oral solution?

SOLTAMOX oral solution is a sugar-free, clear colorless liquid, with licorice and aniseed odor and taste. It is supplied in a 150 mL bottle with a dosing cup intended for the measurement of SOLTAMOX oral solution only. Each 10 mL of solution contains 20 mg tamoxifen, equivalent to 30.4 mg tamoxifen citrate.

What is soltamox used for in breast cancer?

Soltamox is indicated: for the adjuvant treatment of adult patients with early stage estrogen receptor-positive breast cancer. to reduce the occurrence of contralateral breast cancer in adult patients when used as adjuvant therapy for the treatment of breast cancer.

How many mg of tamoxifen are in soltamox?

SOLTAMOX oral solution: Each 10 mL of solution contains 20 mg tamoxifen, equivalent to 30.4 mg tamoxifen citrate. SOLTAMOX oral solution: Each 10 mL of solution contains 20 mg tamoxifen, equivalent to 30.4 mg tamoxifen citrate.

What are the side effects of soltamox?

Soltamox may also be used for purposes not listed in this medication guide. Taking Soltamox may increase your risk of uterine cancer, liver cancer, stroke, or a blood clot in the lung, which can be fatal.