What is latex Immunoturbidimetry?
Latex Enhanced Immunoturbidimetric Assay for Wide-Range, High-Sensitive C-Reactive Protein Detection in Human Serum. Ajaikumar Sukumaran, Thushara Thomas, Deepa K Vijayan, Jofy K Paul. The C-reactive protein is a pentameric, annular, acute phase protein encoded by the chromosome-1 in humans.
What is Immunoturbidimetry test?
Immunoturbidimetry and nephelometry both measure the turbidity of a sample to determine the level of an analyte. Upon addition of the assay reagent, antibodies and antigen cluster to form an immune complex that precipitates, increasing the turbidity of the sample.
Why is Immunoturbidimetry test done?
Turbidimetry (immunoturbidimetry) and nephelometry (immunonephelometry) measurements are commonly used to quantify immune-complex precipitates by their ability to interact with incident light.
Is Immunoturbidimetry an immunoassay?
Immunoturbidimetry and immunonephelometry are widely used immunoassays, especially popular in human clinical biochemistry for the determination of specific proteins. The methods are fast (just a few minutes) and easy to automate, but it is only suitable for protein concentrations above 5 mg/liter.
What is quantitative Immunoturbidimetry?
A quantitative immunoturbidimetric assay for rheumatoid factors (RF) is described, based on the immunoprecipitation between aggregated human IgG and rheumatoid factors in serum. The resulting turbidity is measured photometrically at 340 nm.
Why would hs CRP be high?
High-sensitivity C-reactive protein is produced by the body when blood-vessel walls are inflamed. The higher your levels of hs-CRP, the higher your levels of inflammation tend to be. But before we go any further, it’s important to distinguish between acute inflammation and chronic inflammation.
What is the difference between hs-CRP and CRP?
Defining hs-CRP To illustrate the difference between CRP and hs-CRP, traditional testing measures CRP within the range of 10 to 1,000 mg/L, whereas hs-CRP values range from 0.5 to 10 mg/L. In simpler terms, hs-CRP measures trace amounts of CRP in the blood.