What is detox surgery?
Rapid detox is a method that is designed to rid the patient’s body of physical drug dependency without any conscious awareness of withdrawal symptoms. The detox takes place in a surgical center and the patient is in and out in just a few days. The actual detoxification takes place while the patient is under sedation.
What does ultra rapid mean?
Definition of ultrarapid : marked by an extremely fast rate of motion, activity, succession, or occurrence : extremely or extraordinarily rapid ultrarapid heating/cooling a battery that supports ultrarapid charging.
What is metabolized by CYP2C19?
CYP2C19 catalyzes the metabolism of several drugs, including proton pump inhibitors (PPIs) (e.g., omeprazole, lansoprazole, pantoprazole), antidepressants (e.g., citalopram and amitriptyline), antiplatelet drugs (e.g., clopidogrel), antifungals (e.g., voriconazole), and anticancer compounds (e.g., cyclophosphamide).
Is paroxetine metabolized by CYP2C19?
These are primarily in the cytochrome (CYP) P450 family, and include CYP1A2, CYP2C19, CYP2D6 and CYP3A4. CYP2D6 is involved in the metabolism of most antidepressants, and is primarily responsible for breakdown of amitriptyline, venlafaxine, fluoxetine and paroxetine among others.
Who is a CYP2C19 poor metabolizer?
Individuals who carry 2 non-functional copies of the CYP2C19 gene are classified as CYP2C19 poor metabolizers. They have no enzyme activity and cannot activate clopidogrel via the CYP2C19 pathway, which means the drug will have no effect.
What is CYP2C19 rapid metabolizer?
In people who are rapid metabolizers, the CYP2C19 enzyme has high activity. People who are rapid metabolizers break down some medicines quickly and may need different doses or a different medicine. About 29% of our patients are rapid metabolizers.
Is paroxetine the strongest antidepressant?
Paroxetine is the most potent inhibitor of the reuptake of serotonin of all selective serotonin reuptake inhibitors (SSRIs) and has been studied in many randomised controlled trials (RCTs).