What is amphotericin B used to treat?

What is amphotericin B used to treat?

Amphotericin B injection is used to treat serious and potentially life-threatening fungal infections. Amphotericin B injection is in a class of medications called antifungals. It works by slowing the growth of fungi that cause infection.

How do you administer fungizone?

Fungizone should be administered by intravenous infusion over a period of 2-6 hours. Reduction of the infusion rate may reduce the incidence of side-effects. Initial daily dose should be 0.25 mg/kg of body weight gradually increasing to a level of 1.0 mg/kg of body weight depending on individual response and tolerance.

What is amphotericin B liposomes used for?

Amphotericin B liposomal complex is an antifungal and an antiprotozoal medicine. It is used to help the body overcome serious infections caused by fungus or protozoa.

Can amphotericin B be given orally?

Amphotericin B can be given intravenously, orally or topically. It is not absorbed at all after oral or topical administration and so this mode of delivery is simply for prophylaxis or the treatment of mucosal infection.

How is amphotericin B given?

How to use Amphotericin B Vial. This medication is usually given by injection into a vein as directed by your doctor, usually given once a day or every other day. It should be injected slowly over 2 to 6 hours. Your doctor may give you a smaller dose first to test your response to the medication.

What is amphotericin B side effects?

More common

  • Fever and chills.
  • headache.
  • increased or decreased urination.
  • irregular heartbeat.
  • muscle cramps or pain.
  • nausea.
  • pain at the place of injection.
  • unusual tiredness or weakness.

How do you give an amphotericin B injection?

What does fungizone treat?

Fungizone is a prescription medicine used to treat the symptoms of fungal infections, Cryptococcal Meningitis and Visceral Leishmaniasis. Fungizone may be used alone or with other medications. Fungizone belongs to a class of drugs called Antifungals, Systemic.

What is the major side effect of amphotericin B?

The principal acute toxicity of AmB deoxycholate includes nausea, vomiting, rigors, fever, hypertension or hypotension, and hypoxia. Its principal chronic adverse effect is nephrotoxicity. AmB probably produces renal injury by a variety of mechanisms.

What is liposomal injection used for?

Amphotericin B liposomal injection is used to treat fungal infections such as cryptococcal meningitis (a fungal infection of the lining of the spinal cord and brain) and visceral leishmaniasis (a parasitic disease that usually affects spleen, liver, and bone marrow) in certain people.

How do you inject amphotericin B?

How do you dilute amphotericin B?

Dilute each ‘mg’ of drug with 10 ml. [1 mg/ 10 ml ] [4 – 6 hours] * dilute the reconstituted solution with 250-500 mL D5W; final concentration should not exceed 0.1 mg/mL (peripheral infusion) or 0.25 mg/mL (central infusion). Add 10 mL of SWFI (without a bacteriostatic agent) to each vial of amphotericin B.