What are the contraindications of antiviral drugs?

What are the contraindications of antiviral drugs?

Combined antiviral treatment (Pegylated interferon plus Ribavirin) is contraindicated in instances of:

• decompensate psychiatric disease,
• decompensate diabetes mellitus,
• decompensate arterial hypertension,
• decompensate hemoglobinopathy,
• decompensate autoimmune diseases,

What does SELZENTRY treat?

Maraviroc (brand name: Selzentry) is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults and children weighing at least 4.4 lb (2 kg). Maraviroc is always used in combination with other HIV medicines.

What is the mechanism of action of maraviroc?

Maraviroc selectively binds to the human chemokine receptor CCR5 present on the membrane of CD4 cells (T-cells), preventing the interaction of HIV-1 gp120 and CCR5 necessary for CCR5-tropic HIV-1 to enter cells.

What antiviral drugs are used for the flu?

There are four FDA-approved antiviral drugs recommended by CDC to treat flu this season.

• oseltamivir phosphate (available as a generic version or under the trade name Tamiflu®),
• zanamivir (trade name Relenza®)
• peramivir (trade name Rapivab®), and.
• baloxavir marboxil (trade name Xofluza®).

What do antiviral drugs interfere with?

An antibiotic can usually treat many different types of bacterial infections. But the drugs do not affect viruses. Each antiviral only works against a specific virus. Because viruses inside cells are harder to target, antiviral drugs are more challenging to develop.

What are the side effects of selzentry?

Common side effects of Selzentry include stomach pain, diarrhea, constipation, tiredness, lightheadedness or dizziness while standing, cold symptoms (stuffy nose, sneezing, cough, sore throat), sleep problems (insomnia), swelling, problems with urination, muscle or joint pain, or skin rash.

How do you take selzentry?

SELZENTRY tablets and oral solution are taken twice daily by mouth and may be taken with or without food. SELZENTRY must be given in combination with other antiretroviral medications. The recommended dosage of SELZENTRY differs based on concomitant medications due to drug interactions.

Is maraviroc an antiviral?

Maraviroc 300 Mg Tablet Antiviral-HIV (Antiretroviral) CCR5 Co-Receptor Antagonist – Uses, Side Effects, and More.

What result is required for maraviroc to be considered appropriate for use?

Maraviroc is indicated for treatment of adults with CCR-5 tropic HIV-1 only and is not recommended for adults in whom CXCR4-tropic virus has been detected. The FDA states that tropism testing with a highly sensitive tropism assay is required for the appropriate use of maraviroc (1).