Can naltrexone be used with acamprosate?

Can naltrexone be used with acamprosate?

The synergistic effect of combined treatment remained after 12 weeks of drug-free follow-up. Conclusions: The combination of acamprosate with naltrexone in a clinical sample seems to be efficacious and safe.

Is naltrexone or acamprosate better?

Naltrexone and acamprosate are both safe and effective treatments for alcohol dependence in adults. Acamprosate improves adherence and abstinence rates, whereas naltrexone significantly reduces relapse rates, time to relapse, and frequency of drinking.

Does naltrexone interfere with other medications?

Some products that may interact with this drug include: dextromethorphan, diarrhea medication (such as diphenoxylate), disulfiram, opioid pain or cough relievers (such as codeine, hydrocodone), thioridazine.

Does naltrexone interfere with antidepressants?

Common medications that may interact with naltrexone include: disulfiram, used in the management of alcohol abuse. all medications that have sedation as a side effect, including antidepressants, first-generation antihistamines, antipsychotics, anti-anxiety medications.

Does naltrexone help with anxiety?

Importance: Extended-release naltrexone (XR-NTX) is a promising alternative treatment of opioid addiction but has never been compared with opioid agonist treatment for effects on symptoms of anxiety, depression, and insomnia.

Can naltrexone cause serotonin syndrome?

The risk or severity of serotonin syndrome can be increased when Naltrexone is combined with Almotriptan. The risk or severity of adverse effects can be increased when Naltrexone is combined with Alprazolam.

Can naltrexone make depression worse?

Participants who received naltrexone did not exhibit worsening of depressive symptoms. In participants attending all follow-up assessments, there was a trend for those receiving naltrexone to exhibit an improvement in depression over time compared with the control group.