Is malonaldehyde a dialdehyde?

Is malonaldehyde a dialdehyde?

Malonaldehyde is a dialdehyde that is propane substituted by two oxo groups at the terminal carbon atoms respectively. A biomarker of oxidative damage to lipids caused by smoking, it exists in vivo mainly in the enol form.

Is malonaldehyde a carcinogen according to NIOSH?

NIOSH considers malonaldehyde to be a potential occupational carcinogen. NIOSH. NIOSH Pocket Guide to Chemical Hazards. DHHS (NIOSH) Publication No. 97-140. Washington, D.C. U.S. Government Printing Office, 1997., p. 190 Ca [N.D.] A harmful concentration of airborne particles can be reached quickly.

What happens when malonaldehyde reacts with DNA?

Malonaldehyde reacts with DNA to form an adduct with 2′-deoxyguanosine with has been characterized as 3- (2-deoxy-beta-D-erythro-pentofuranosy)pyrimido (1,2-alpha)purin-10 (3H)-one ( M1G-dR ). This adduct is present at quantifiable levels in DNA from many human tissues.

What is malondialdehyde CH2 (CHO2)?

Malondialdehyde is an organic compound with the formula CH2 (CHO)2, and a byproduct of lipid metabolism in the body. Malondialdehyde, a highly reactive compound, is one of the many reactive electrophile species that cause toxic stress in cells and form covalent protein adducts, called advanced lipoxidation end products (ALE).