How do I reconstitute 1g cefepime?
For IM injection, reconstitute vial containing 500 mg or 1 g of cefepime with 1.3 or 2.4 mL, respectively, of sterile water for injection, 0.9% sodium chloride, 5% dextrose, 0.5 or 1% lidocaine hydrochloride, or bacteriostatic water for injection (with parabens or benzyl alcohol) to provide a solution containing …
How do you administer cefepime IV?
Cefepime injection comes as a powder to be mixed with liquid, or as a premixed product, to be injected intravenously (into a vein) over a period of 30 minutes. Cefepime injection can also be given intramuscularly (into a muscle). It is usually given every 8 or 12 hours for 7 to 10 days.
How fast can you administer cefepime in or?
Cefepime for Injection USP and Dextrose Injection USP should be administered intravenously (IV) over approximately 30 minutes. The maximum dose for pediatric patients should not exceed the recommended adult dose.
How do you reconstitute cefepime for IV?
Reconstitute vial with 20 mL sterile water for injection or 0.9% sodium chloride and further dilute to 50-150 mL. Maximum recommended volume per dose of sterile water for injection is 50 mL. Cannot be administered by IV push. Administer over at least 30 minutes.
What can you mix cefepime with?
Intramuscular Administration: For IM administration, MAXIPIME (cefepime hydrochloride) should be constituted with one of the following diluents: Sterile Water for Injection, 0.9% Sodium Chloride, 5% Dextrose Injection, 0.5% or 1.0% Lidocaine Hydrochloride, or Sterile Bacteriostatic Water for Injection with Parabens or …
Does cefepime cover Gram-positive?
CLINICAL PHARMACOLOGY Cefepime is an antibacterial agent belonging to the cephalosporin class of antibacterials with in vitro antibacterial activity against facultative Gram-positive and Gram-negative bacteria.
How fast can you infuse cefazolin?
Cefazolin 2 g Powder for solution for injection/infusion: Should not be used for intramuscular administration. Cefazolin is to be injected slowly over three to five minutes. In no case should the solution be injected in less than 3 minutes.
Which is better cefepime or ceftriaxone?
Although a larger study is required to assess the comparative efficacies of cefepime and ceftriaxone against pneumonia caused by gram-negative bacteria or pathogens resistant to multiple antimicrobial agents, in vitro studies have demonstrated that cefepime’s activity against certain key gram-negative pathogens.
What is the pH of cefepime?
The L-arginine, at an approximate concentration of 725 mg/g of cefepime, is added to control the pH of the constituted solution at 4.0–6.0.
What is the dosage for cefepime?
Cefepime Dosage and Administration. Constitute Cefepime for injection vials 1 gram and 2 grams with one of the following diluents: Sterile Water for Injection, 0.9% Sodium Chloride, 5% Dextrose Injection, 0.5% or 1% Lidocaine Hydrochloride, or Sterile Bacteriostatic Water for Injection with Parabens or Benzyl Alcohol.
What are the diluents in cefepime?
Constitute Cefepime for Injection vials 0.5 gram, 1 gram and 2 grams with one of the following diluents: Sterile Water for Injection, 0.9% Sodium Chloride, 5% Dextrose Injection, 0.5% or 1% Lidocaine Hydrochloride, or Sterile Bacteriostatic Water for Injection with Parabens or Benzyl Alcohol.
What is the equivalent of 825 MCG of cefepime in MG?
Cefepime hydrochloride contains the equivalent of not less than 825 mcg and not more than 911 mcg of Cefepime (C 19 H 24 N 6 O 5 S 2) per mg, calculated on an anhydrous basis. It is highly soluble in water. Cefepime for Injection, USP is supplied for intramuscular or intravenous administration in strengths equivalent to 1 g, and 2 g of Cefepime.
How do you prepare cefepime for intramuscular administration?
Preparation for Intramuscular Administration Constitute Cefepime for injection vials 1 gram and 2 grams with one of the following diluents: Sterile Water for Injection, 0.9% Sodium Chloride, 5% Dextrose Injection, 0.5% or 1% Lidocaine Hydrochloride, or Sterile Bacteriostatic Water for Injection with Parabens or Benzyl Alcohol.