When should ERIG be given?
Rabies immunoglobulin (RIG) should be administered as soon as possible after the initiation of post-exposure prophylaxis. RIG should not be given after day 7 following the first rabies vaccine dose, because circulating neutralizing antibody will have begun to appear.
What is ERIG vaccine for?
ERIG is equine RIG and is produced in horses. HRIG is human RIG and is produced in humans. Both products contain antibodies specifically made against rabies virus. Both products are produced by vaccinating horses (ERIG) or humans (HRIG) and harvesting their plasma which contains antibodies against rabies virus.
When do you give ERIG vaccine?
As equine rabies immunoglobulin (ERIG): 40 IU/kg. Administer as a single dose on the 1st day of rabies vaccine (or within 7 days after) via infiltration into and around the cleansed wound.
Does ERIG need skin test?
Background: Rabies immunoglobulins are life-saving in patients with severe exposure to rabies. Despite the high degree of purification of equine rabies immunoglobulin (ERIG), the product inserts still recommend a skin sensitivity test before administration of this heterologous serum.
What are the side effects of ERIG?
Erig Injection is a Injection manufactured by NEWGEN CADILA PHARMA. It is commonly used for the diagnosis or treatment of rabies . It has some side effects such as Swollen lymph node,Reddening and swelling at injection site,Joint pains. The salts Vaccine Rabies are involved in the preparation of Erig Injection.
How much is ERIG?
The average volume of eRIG used per patient was 0.75 mL and cost US$ 0.75.
What are the side effects of eRIG?
How much is eRIG?
Which is better HRIG or ERIG?
Human rabies immunoglobulin (HRIG) is preferable when it is available. If it is not, equine rabies immunoglobulin (ERIG) is also effective to neutralize virus. The dose of HRIG is 20 IU/kg of body weight. For ERIG, the dose is 40 IU/kg because ERIG has a shorter half-life.
Is ERIG vaccine painful?
There were no serious systemic side-effects but local side-effects like induration, erythema, pruritus are due to the intradermal rabies vaccination (IDRV) and pain, induration due to ERIG.
How do you calculate ERIG?
ERIG/ F(ab’)2 at 40 IU/kg. body weight (200 IU/ml) 50 kg. patient x 40 IU/kg. = 2000 IU 2000 IU รท 200 IU/ml = 10 ml.