What is glycogen in the vagina?

What is glycogen in the vagina?

Glycogen is produced by vaginal and cervical epithelial cells and has been recognized as temporally associated with colonization and growth of Lactobacillus in the lower genital tract [12]. Thus, when epithelial glycogen is low, as in pre-puberty and post-menopause, Lactobacillus levels are also low [12].

What does Megasphaera 1 mean?

LP140228-0 Megasphaera sp type 1. Bacterial vaginosis (BV) is the most common vaginal infection, occurring when there is an overgrowth of anaerobic bacteria in the vagina.

What is the function of Lactobacillus in vagina?

It is broadly suggested that the crucial role of vaginal lactobacilli is to protect female genital tract through the production of lactic acid responsible for low vaginal pH that inhibits sexually transmitted pathogens. Lactic acid is in equilibrium with lactate anion.

What is vaginal Eubiosis?

Vaginal eubiosis is characterised by the presence of beneficial lactic-acid-producing microbiota predominantly from the genus Lactobacillus. Lactobacillus spp., naturally or administered as probiotics, may establish vaginal eubiosis by killing dysbiotic microbes, and many types of pathogens, with acidic lactic acid.

Does vaginal fluid contain glucose?

Results: In healthy women, the median level of glucose in vaginal secretions was 5.2 mM before and 3.7 mM after oral glucose tolerance test, and plasma glucose was 5.0 mM before and 5.8 mM after oral glucose tolerance test.

Is Megasphaera the same as BV?

Megasphaera Type 2 was not found to be highly prevalent in this patient cohort, however the presence of this organism is highly specific for BV. Lactobacillus jenseniiare Gram-positive, rod-shaped, facultative anaerobic non-spore forming bacteria and common members of healthy vaginal bacterial microflora.

Does estrogen increase Lactobacillus?

Specifically, rising estrogen levels increase available glycogen in the vaginal epithelium, which in turn, provides an energy source for lactobacilli to produce lactic acid.

How can I restore my vaginal microbiome?

Currently, well-characterised probiotic bacteria, such as combination of Lactobacillus rhamnosus HN001 and Lactobacillus acidophilus La-14, can be used for maintaining healthy vaginal microbiota or restoring normal microbiota after antibiotic treatment. Probiotics may elicit beneficial effects in several ways.

How can I improve my vaginal microbiota?

Does diet affect vaginal microbiome?

Emerging evidence suggests that higher quality diets may be associated with lower risk of BV. Effects on BV might be mediated through direct effects in the vagina or via an impact of diet or specific micronutrients on the gut microbiota.