What is NAB-paclitaxel gemcitabine?

What is NAB-paclitaxel gemcitabine?

Gemcitabine and nab-paclitaxel (Abraxane®) is used to treat advanced cancer of the pancreas.

Does NAB-paclitaxel cause hair loss?

You could lose all your hair. This includes your eyelashes, eyebrows, underarm, leg and sometimes pubic hair. Your hair will usually grow back once treatment has finished but it is likely to be softer. It may grow back a different colour or be curlier than before.

How effective is nab-paclitaxel?

Patients ≥65 years (median: 69) were analyzed. In phase 2 (n = 52), overall response rates (ORR) for weekly nab-paclitaxel were 60–64% vs 22% for q3w nab-paclitaxel and 32% for docetaxel.

Is nab-paclitaxel a Vesicant?

This clinical procedure outlines the management of an extravasation with the following drugs that are known to be irritants with vesicant properties; bendamustine, docetaxel, liposomal doxorubicin, melphalan, mitozantrone, oxaliplatin, paclitaxel or nab-paclitaxel.

How effective is gemcitabine?

Since 1997, gemcitabine therapy has been the standard first-line treatment for patients with unresectable locally advanced or metastatic pancreatic cancer. Among patients with metastatic disease, the 5-year survival rate is only 2%,1 and 1-year survival rates of 17 to 23% have been reported with gemcitabine.

Is paclitaxel an irritant or vesicant?

Chemotherapy vesicant & irritant properties and suggested management for extravasation

Is Abraxane better than paclitaxel?

The researchers concluded that these results confirm those of previous studies evaluating Abraxane and provide further evidence that Abraxane is superior to Taxol in terms of anticancer response and cancer progression. Furthermore, Abraxane is better tolerated than Taxol and does not require intravenous premedication.