What does Stot Se 3 mean?

What does Stot Se 3 mean?

STOT SE consists of three hazard categories – STOT SE 1 (H370, signal word “Danger”), STOT SE 2 (H371, signal word “Warning”) und STOT SE 3 (signal word “Warning”). STOT SE 1 means definitely toxic to humans from single exposure, also determined on the basis of animal experiments.

What are target organs on SDS?

Most of the organs and systems in the body can be a target, but the most commonly referred to as a target organ when reading a safety data sheet are: Lungs, liver, kidney, heart, blood, or circulatory system, brain or central nervous system, and skin (yes, the skin is considered an organ.)

What are the main elements of GHS safety?

Core elements of the GHS include standardized hazard testing criteria, universal warning pictograms, and harmonized safety data sheets which provide users of dangerous goods with a host of information. The system acts as a complement to the UN Numbered system of regulated hazardous material transport.

What does target organs mean in chemistry?

Target organ toxins are chemicals that can cause adverse effects or disease states manifested in specific organs of the body.

What is organ specific toxicity?

Specific target organ toxicity (single exposure) (STOT-SE) means specific non-lethal effects on organs or organ systems in the body following single exposure to a chemical.

Why is the liver a target organ for toxicity?

Because of its fundamental anatomy, high metabolic potential, and ability to clear xenobiotics from the blood, the liver represents an organ with a high susceptibility to the toxic effects of chemical–chemical interactions.

What is the target organ of hepatitis?

Hepatitis is a viral disease that targets the liver of the human.

What is the target organ of jaundice?

Jaundice is often a sign of a problem with the liver, gallbladder, or pancreas. Jaundice can occur when too much bilirubin builds up in the body. This may happen when: There are too many red blood cells dying or breaking down and going to the liver.

What causes organ toxicity?

The use, particularly when repeated, of many drugs can lead to an accumulation of a drug, or harmful byproducts from the metabolism of a drug, in tissues or organs. This accumulation of toxic chemicals can lead to organ damage, and in extreme cases, even organ failure and death.