Is dofetilide a REMS drug?

Is dofetilide a REMS drug?

Under the REMS program, Tikosyn (dofetilide) could only be prescribed by enrolled prescribers and dispensed by enrolled pharmacies and healthcare facilities.

What drug tier is dofetilide?

What drug tier is dofetilide typically on? Medicare prescription drug plans typically list dofetilide on Tier 4 of their formulary. Generally, the higher the tier, the more you have to pay for the medication.

When was dofetilide approved by the FDA?

Approval Date: 10/1/1999.

When did Tikosyn go generic?

On June 7, 2016, Mayne Pharma announced the launch of an AB-rated generic version of Pfizer’s Tikosyn (dofetilide) 0.125 mg, 0.25 mg, and 0.5 mg capsules.

Is dofetilide a blood thinner?

Dofetilide is known as an anti-arrhythmic drug. It works by blocking the activity of certain electrical signals in the heart that can cause an irregular heartbeat. Treating an irregular heartbeat can decrease the risk for blood clots, and this effect can reduce your risk of heart attack or stroke.

Is procainamide a calcium-channel blocker?

Procainamide (PCA) is a medication of the antiarrhythmic class used for the treatment of cardiac arrhythmias. It is classified by the Vaughan Williams classification system as class Ia; thus it is a sodium channel blocker of cardiomyocytes.

Is procainamide a calcium channel blocker?

Does dofetilide decrease potassium?

Dofetilide is a class III antiarrhythmic agent. By inhibiting a component of the time-dependent potassium current, dofetilide increases the effective refractory period and action potential without affecting the conduction velocity.

Is dofetilide generic for Tikosyn?

Tikosyn is available as a generic drug called dofetilide. A generic drug is an exact copy of the active drug in a brand-name medication. The generic is considered to be as safe and effective as the original drug.

What should I monitor with dofetilide?

Monitor for ECG changes if therapy is initiated in patients with drugs known to prolong QT interval. dofetilide and panobinostat both increase QTc interval. Avoid or Use Alternate Drug. Panobinostat is known to significantly prolong QT interval.