What drugs are used in triple therapy?

What drugs are used in triple therapy?

Over the last two decades, the recommended first-line treatment for the eradication of H. pylori has been the standard triple therapy, comprising a PPI, amoxicillin and clarithromycin or metronidazole[11,12].

How does bismuth work for H. pylori?

Bismuth exerts direct bactericidal effect on Helicobacter pylori by different ways: forms complexes in the bacterial wall and periplasmic space, inhibits different enzymes, ATP synthesis, and adherence of the bacteria to the gastric mucosa.

Can amoxicillin alone treat H. pylori?

Despite being secreted into the gastric juice and mucosa during oral therapy, amoxicillin by itself achieves less than a 20% eradication rate of H pylori. More than 2 g a day of amoxicillin does not increase its eradication rate of H pylori when used as a single agent.

How do you take bismuth quadruple therapy?

Completely chew and swallow 2 bismuth tablets. Swallow the metronidazole tablets and tetracycline capsules with a full glass (8 ounces) of water. Do not chew, crush, or break the metronidazole tablets and tetracycline capsules. Take this medicine with meals and at bedtime.

What is the fastest way to cure H. pylori?

The options include:

1. Antibiotics to kill the bacteria in your body, such as amoxicillin, clarithromycin (Biaxin), metronidazole (Flagyl), tetracycline (Sumycin), or tinidazole (Tindamax).
2. Drugs that reduce the amount of acid in your stomach by blocking the tiny pumps that produce it.

When should I take bismuth for H. pylori?

For H. pylori infection and duodenal ulcer (taken with an H2 blocker): Adults—One dose (two 262.4 milligrams [mg] of bismuth subsalicylate, one 250 mg of metronidazole, and one 500 mg of tetracycline) 4 times a day, taken with meals and at bedtime, for 14 days. Children—Use and dose must be determined by your doctor.

How do you take bismuth Subcitrate?

Administer three PYLERA capsules 4 times a day (after meals and at bedtime) for 10 days. One omeprazole 20 mg capsule should be taken twice a day with PYLERA after the morning and evening meal for 10 days (Table 1). Instruct patients to swallow the PYLERA capsules whole with a full glass of water (8 ounces).

Is yogurt good for H. pylori?

Abstract. Background: Evidence suggests that ingesting lactic acid bacteria exerts a suppressive effect on Helicobacter pylori infection in both animals and humans. Supplementing with Lactobacillus- and Bifidobacterium-containing yogurt (AB-yogurt) was shown to improve the rates of eradication of H. pylori in humans.