What is DIC in obstetrics?
Disseminated intravascular coagulation (DIC) is a syndrome that can be initiated by a myriad of medical, surgical, and obstetric disorders. Also known as consumptive coagulopathy, DIC is a common contributor to maternal morbidity and mortality and is associated with up to 25% of maternal deaths.
What is DIC in nursing?
Disseminated intravascular coagulation (DIC) is a coagulation disorder that prompts overstimulation of the normal clotting cascade and results in simultaneous thrombosis and hemorrhage. The formation of microclots affects tissue perfusion in the major organs, causing hypoxia, ischemia, and tissue damage.
What is DIC during labor?
Disseminated intravascular coagulation (DIC) is an acquired syndrome characterised by systemic intravascular activation of coagulation. There are several obstetric causes of DIC during pregnancy and postpartum.
What is the most common cause of DIC in pregnancy?
Disseminated intravascular coagulation can be brought about by a number of obstetric complications, including acute peripartum hemorrhage, placental abruption, preeclampsia, elevated liver enzymes/low platelet count syndrome, retained stillbirth, septic abortion, intrauterine infection, amniotic fluid embolism, and …
What is DIC medical?
Disseminated intravascular coagulation (DIC) is a serious disorder in which the proteins that control blood clotting become overactive.
How DIC occurs in preeclampsia?
The DIC syndrome is the most common cause of an abnormal hemorrhage tendency during pregnancy and the puerperium and reflects systemic activation of the coagulation cascade by circulating thromboplastic material, with secondary activation of the fibrinolytic system.
What are the causes of DIC in obstetrics?
The identified causes of obstetrical DIC were placental abruption (18; 37%), postpartum hemorrhage (14; 29%), preeclampsia (7; 14%), acute fatty liver of pregnancy (4; 8%), sepsis (3; 6%), and AFE (3; 6%). The ISTH scores were unavailable in 22 of the 49 cases, usually because of the lack of fibrinogen value.
Can cesarean cause DIC?
A typical case of DIC presumably precipitated by cesarean section done for severe toxemia of pregnancy is reported. A laboratory study followed up the progress of DIC, especially of the drop in the consumptive platelet count and fibrinogen level as a result of excessive blood clotting.
What complications may predispose a pregnant woman to DIC?
This life-threatening condition is a complication of obstetrical and non-obstetrical causes including: (1) acute peripartum hemorrhage (uterine atony, cervical and vaginal lacerations, and uterine rupture); (2) placental abruption; (3) Pre-eclampsia/HELLP syndrome; (4) retained stillbirth; (5) sepsis; (6) amniotic …
How common is DIC in pregnancy?
As there is no single diagnostic test for DIC and there is a spectrum of clinical severity, the true incidence of obstetrical DIC is not known. Retrospective studies have reported the incidence to range from 0.02% to 0.07% of all pregnancies.