What is significant about Mycobacterium smegmatis?
The HR pathway of M. smegmatis is the major determinant of resistance to ionizing radiation and oxidative DNA damage. This pathway involves exchange of information between a damaged chromosome and another homologous chromosome in the same cell.
How do you identify Mycobacterium smegmatis?
Mycobacterium smegmatis is a Gram-positive bacteria, characterized by an inner cell membrane and a thick cell wall. The Gram-positive bacteria is further classified as one with a high GC content and therefore a low AT content. This quality is used as a crude measure of similarity of different species of bacteria.
How do you treat Mycobacterium smegmatis?
The most effective treatment for M. smegmatis infections of skin, soft tissue, and bone is a combined regime of prolonged antibiotic therapy and surgical debridement. Although M. smegmatis is resistant to isoniazid and rifampin, it is susceptible to ethambutol.
Is Mycobacterium smegmatis infectious?
Mycobacterium smegmatis is an uncommon pathogen in humans that has been associated predominantly with skin and soft tissue infections. Osteomyelitis secondary to direct extension from a surgical or posttraumatic wound has been described.
What causes smegmatis?
Newton and Weiss are correct that Mycobacterium smegmatis can cause human infection, particularly in a lipid- rich environment such as aspiration pneumonitis associated with achalasia. M. smegmatis, one of the rapid-growing mycobacteria, is an environmental species. It is similar to and has been confused with M.
What is the arrangement of Mycobacterium smegmatis?
Mycobacterium smegmatis str. MC2 155
| Names | Mycobacterium smegmatis str. MC2 155 |
|---|---|
| Cell arrangement | Singles |
| Sporulation | Nonsporulating |
| Metabolism | NA |
| Energy source | Chemoorganotroph |
Is Mycobacterium smegmatis aerobic or anaerobic?
aerobic
smegmatis is found to non-pathogenic and rapidly developing than other Mycobacterium species [3]. The organism is aerobic, which donates the final electrons to oxygen during respiration. The maximum amount of energy for this bacteria will be obtained by oxidative phosphorylation.
What color is Mycobacterium smegmatis?
What color is Mycobacterium smegmatis in an acid fast stain? Why? It is red because it is acid fast positive. The carbolfuchsin is more soluble in the cell wall lipids therefore, retains the red color.
What infection does Mycobacterium smegmatis cause?
Drs. Newton and Weiss are correct that Mycobacterium smegmatis can cause human infection, particularly in a lipid- rich environment such as aspiration pneumonitis associated with achalasia.
Is Mycobacterium smegmatis Gram positive or negative?
Bacteria, Gram-Positive This bacteria is an acid-fast, bacillus-shaped, aerobic microorganism that is commonly used a surrogate model for M. tuberculosis and is found in soil, plants, and water.
What is the morphology of Mycobacterium smegmatis?
The surface morphology of this microbe will be shiny, smooth, finely wrinkled or coarsely collapsed [2]. M. smegmatis is found to non-pathogenic and rapidly developing than other Mycobacterium species [3]. The organism is aerobic, which donates the final electrons to oxygen during respiration.
Do mycobacteria have a cell wall?
The distinguishing feature of mycobacteria, the complex cell wall, is a well-recognized drug target. The cell wall is common to all bacteria, both Gram-positive and Gram-negative, but can have vast differences in terms of the biochemical and structural features.