What is monograph in USP?
A monograph is a written document that reflects the quality attributes of medicines approved by the U.S. Food and Drug Administration (US FDA). Some of these attributes include: Identity – Tests to identify that a particular substance is the medicine that it claims to be.
What class of drug is lumefantrine?
Artemether and lumefantrine is in a class of medications called antimalarials. It works by killing the organisms that cause malaria.
What is the chemical name for lumefantrine?
Artemether and lumefantrine
| PubChem CID | 6450800 |
|---|---|
| Molecular Formula | C46H58Cl3NO6 |
| Synonyms | artemether + lumefantrine Artemether and lumefantrine 141204-94-6 Co-Artemether Exafal More… |
| Molecular Weight | 827.3 |
| Component Compounds | Active Ingredients in Mixture Drug ARTEMETHER; LUMEFANTRINE CID 6437380 (Lumefantrine) CID 456408 |
What is monograph in?
noun. a treatise on a particular subject, as a biographical study or study of the works of one artist. a highly detailed and thoroughly documented study or paper written about a limited area of a subject or field of inquiry: scholarly monographs on medieval pigments.
Why is artemether combined with lumefantrine?
Artemether is administered in combination with lumefantrine for improved efficacy. Artemether has a rapid onset of action and is rapidly cleared from the body. It is thought that artemether provides rapid symptomatic relief by reducing the number of malarial parasites.
What is another name for artemether and lumefantrine?
Artemether/lumefantrine, sold under the trade name Coartem among others, is a combination of the two medications artemether and lumefantrine. It is used to treat malaria caused by Plasmodium falciparum that is not treatable with chloroquine.
Which medicine is best for malaria?
Medications. The most common antimalarial drugs include: Chloroquine phosphate. Chloroquine is the preferred treatment for any parasite that is sensitive to the drug.
What is the half life of lumefantrine?
Lumefantrine has an elimination half-life of approximately six days in healthy volunteers [8] and three to four days in patients with Plasmodium falciparum malaria [7,9] (Table 1).
What is monograph and example?
8. 3. The definition of a monograph is a long, detailed scholarly piece of writing on a specific subject. An example of a monograph is a book on how the human body uses Vitamin D. noun.