How is colorimetry used in aspirin?

How is colorimetry used in aspirin?

The amount of 2-hydroxybenzoic acid in a solution made by hydrolysing aspirin can be determined by adding iron(III) ions and measuring the intensity of the violet-blue solution. From this the amount of aspirin can be calculated.

Does aspirin absorb UV light?

Acetylsalicylic acid, commonly known as aspirin, absorbs light in the UV region of the electromagnetic spectrum. The Spectronic 200 operates in the visible region.

How do you Assay aspirin?

Dissolve ASA sample in 5 ml ethanol 95 % and then add 25 ml of 0.5 N NaOH, the container of the mixture was stoppered and allowed to stand for ½ hour to complete the hydrolysis of ASA. 1-2 drops of bromophenol blue (bpb) indicator was added and the solution was titrated with 0.5 N HCl. The endpoint is pink  colorless.

Which is correct sequence of assay of aspirin?

b) Standard solution. Which is correct sequence of assay of aspirin. a) Aspirin + 2,3 drops of Phenolphthalein+NaOH solution+ethanol.

Is there a colorimetric method for detecting SA in aspirin?

The developed colorimetric method not only has excellent accuracy in detecting SA in aspirin compared with HPLC but also shows high selectivity and sensitivity to SA. In summary, the proposed method can be well-utilized for detecting SA in aspirin.

Can we detect free SA in aspirin by using mil-53 (Fe)?

Since free SA is significantly toxic for humans, the content determination of free SA is absolutely necessary to ensure people’s health. In this work, a facile colorimetric method was developed for the detection of SA in aspirin by utilizing the MIL-53 (Fe) nanozyme.

What is the impurity of salicylic acid in aspirin?

The impurity of salicylic acid (SA) in aspirin is a required inspection item for drug quality control. Since free SA is significantly toxic for humans, the content determination of free SA is absolutely necessary to ensure people’s health.

Can MOFs nanozymes be used to detect SA in aspirin?

In summary, the proposed method can be well-utilized for detecting SA in aspirin. Furthermore, the present work displays the great potential of using MOFs nanozymes for pharmaceutical analysis.