What does a positive SSA and SSB antibody mean?

What does a positive SSA and SSB antibody mean?

A positive result for SSA (Ro) or SSB (La) antibodies is consistent with connective tissue disease, including Sjogren syndrome, lupus erythematosus (LE), or rheumatoid arthritis.

What does SSB antibody mean?

Anti-Sjögren’s syndrome type B (SSB) antibodies are one of the most common autoantibodies in the serum of SLE patients and also one of the earlier autoantibodies to be produced (11–13).

What does high anti SSA mean?

Elevated Sjögren’s antibodies—anti-SS-A and anti-SS-B—are suggestive of inflammatory connective tissue disease. Elevated results on this test may indicate Sjögren’s syndrome or another autoimmune disease such as lupus or rheumatoid arthritis.

What does positive SS-B mean?

A positive result for SS-B/La antibodies is consistent with connective tissue disease, including Sjogren syndrome and lupus erythematosus.

Can you have Sjogren’s syndrome without dry mouth?

Symptoms. Sjögren’s syndrome may affect only the eyes or only the mouth or it may be more general. One out of three people who have Sjögren’s syndrome also have arthritis. A person may have signs of a rheumatic disease, but not have the dry eyes or mouth associated with some forms of Sjögren’s.

What does a positive SS-B mean?

Can you have sjogrens without SS-A and SS-B?

Antibodies against SSA/Ro are found in approximately 50% of patients with the disease (75% of patients with primary Sjögren syndrome and 15% of patients with secondary Sjögren syndrome). Thus, the absence of anti-SSA/Ro antibodies does not eliminate the diagnosis of primary or secondary Sjögren syndrome.

What is SS-B and SSA test?

Anti‐SSA and ‐SSB antibodies are clinically important antinuclear antibody (ANA) in patients with systemic rheumatic diseases. These antibodies are found in Sjögren’s syndrome (SS), as well as other systemic autoimmune diseases (ADs), such as systemic lupus erythematosus (SLE), myositis, scleroderma, etc.