Is Kexin a protease?
Kexin (EC 3.4. 21.61) is a prohormone-processing protease, specifically a yeast serine peptidase, found in the budding yeast (S. cerevisiae).
What type of protease is subtilisin?
serine proteases
Subtilisin is a protease (a protein-digesting enzyme) initially obtained from Bacillus subtilis. Subtilisins belong to subtilases, a group of serine proteases that – like all serine proteases – initiate the nucleophilic attack on the peptide (amide) bond through a serine residue at the active site.
Is subtilisin safe?
In conclusion it can be said, that use of Subtilisin in laundry and cleaning products represents no safety concerns for consumers.
What does the name Kexin mean?
From Chinese 可 (kě) meaning “can, able to, approve, permit” or 克 (kè) meaning “overcome, win” combined with 心 (xīn) meaning “heart, mind, soul”, 新 (xīn) meaning “fresh, new”, 欣 (xīn) meaning “happy, joyous, delighted”, 信 (xìn) meaning “trust, believe”, or 辛 (xīn) meaning “hard, suffering, laborious, tired”.
What does subtilisin do and why is it of commercial interest?
Protein-engineered subtilisins are widely used in commercial products (the native enzyme is easily inactivated by detergents and high temperatures) and is also called a stain cutter, for example, in laundry and dishwashing detergents, cosmetics, food processing, skin care ointments, contact lens cleaners, and for …
What is subtilisin in skincare?
Subtilisins are proteolytic enzymes, mainly (>90 %) used in detergents and household cleaning products to remove proteinaceous deposits and stains.
Is Kexin a Chinese name?
Is Kexin a male or female name?
Kexin – Girl’s name meaning, origin, and popularity | BabyCenter.
What is the Kex2 gene?
The prohormone-processing endoprotease ( KEX2 gene product) of the yeast Saccharomyces cerevisiae is a membrane-bound, 135,000-dalton glycoprotein, which contains both asparagine -linked and serine – and threonine -linked oligosaccharide and resides in a secretory compartment [8].
How is KEX2 protease localized in yeast?
The transmembrane Kex2 protease, which processes precursors of secreted peptides within the yeast secretory pathway, is also localized by indirect immunofluorescence to multiple structures in the yeast cell (Redding, K., and R. Fuller, manuscript submitted for publication) [30].
How do you isolate KEX2 proteinase from cells?
Because KEX2 proteinase is located within the Golgi compartment, it may be isolated by differential centrifugation of broken cells at 7000g for 15 min and at 20,000g for 15 min [35]. Absence of this activity cosegregates with the other phenotypes of a kex2 lesion in genetic crosses [6].
Where does the Kex2 endoprotease of Saccharomyces cerevisiae reside?
The KEX2 -encoded endoprotease of Saccharomyces cerevisiae resides in the Golgi complex where it participates in the maturation of alpha-factor mating pheromone precursor [17].