What does pramipexole do to the body?

What does pramipexole do to the body?

Pramipexole is a dopamine agonist that works on the nervous system to help treat the symptoms of Parkinson disease. Pramipexole is also used to treat Restless Legs Syndrome (RLS). RLS is a neurologic disorder that affects sensation and movement in the legs and causes the legs to feel uncomfortable.

Does pramipexole work immediately?

Pramipexole (Mirapex) is an immediate-release tablet, which means the medication is released in your body soon after you take your dose and it reaches high levels in your body in about 2 hours.

Can you overdose on pramipexole?

Pramipexole overdose with hallucination, agitation, and myoclonus is consistent with adverse effects reported with therapeutic toxicity, but mirtazapine and venlafaxine may have contributed.

Can pramipexole cause liver damage?

Outcome and Management. Instances of liver injury attributed to pramipexole have been mild, asymptomatic and self-limiting. No instances of acute liver failure or chronic injury have been reported.

What are the side effects of pramipexole?

In Summary. Commonly reported side effects of pramipexole include: drowsiness, visual hallucination, constipation, and insomnia. Other side effects include: xerostomia. See below for a comprehensive list of adverse effects.

Is pramipexole dihydrochloride soluble in methanol?

Pramipexole dihydrochloride is more than 20% soluble in water, about 8% in methanol, about 0.5% in ethanol, and practically insoluble in dichloromethane. Pramipexole dihydrochloride tablets, for oral administration, contain 0.125 mg, 0.25 mg, 0.5 mg, 1 mg, or 1.5 mg of pramipexole dihydrochloride monohydrate.

What class of drug is pramipexole?

Pramipexole belongs to a class of drugs called dopamine agonists. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions. Pramipexole works by activating certain receptors in your brain.

How much pramipexole should I take for Parkinson’s disease?

In a fixed-dose study in early Parkinson’s disease patients, doses of 3 mg, 4.5 mg, and 6 mg per day of pramipexole dihydrochloride tablets were not shown to provide any significant benefit beyond that achieved at a daily dose of 1.5 mg/day.