What class of drug is imipenem?

What class of drug is imipenem?

Imipenem is in a class of medications called carbapenem antibiotics. It works by killing bacteria. Cilastatin is in a class of medications called dehydropeptidase inhibitors.

What class of antibiotic is gentamicin?

Gentamicin belongs to the class of medicines known as aminoglycoside antibiotics. It works by killing bacteria or preventing their growth. However, this medicine will not work for colds, flu, or other virus infections.

What class of antibiotics is vancomycin?

Vancomycin is in a class of medications called glycopeptide antibiotics. It works by killling bacteria in the intestines. Vancomycin will not kill bacteria or treat infections in any other part of the body when taken by mouth.

Is imipenem and meropenem the same?

In general, imipenem is more active against Gram-positive cocci while meropenem is more active against Gram-negative bacilli. The agents display similar pharmacokinetics.

Is meropenem penicillin based?

Meropenem is an antibiotic that fights many of the same infections as penicillin. Meropenem may be an option for patients who are allergic to penicillin. However, meropenem and penicillins have similar chemical structures; therefore, doctors often avoid using meropenem in patients who are allergic to penicillin.

What family is meropenem in?

It is in the carbapenem family of medications. Meropenem usually results in bacterial death through blocking their ability to make a cell wall. It is more resistant to breakdown by β-lactamase producing bacteria.

Is gentamicin broad or narrow spectrum?

Gentamicin is the aminoglycoside of choice in the UK and is used widely for the treatment of serious infections. It has a broad spectrum but is inactive against anaerobes and has poor activity against haemolytic streptococci and pneumococci.

Is vancomycin broad or narrow spectrum?

Vancomycin is a broad spectrum antibiotic that has activity against methicillin-resistant strains of Staphylococcus aureus and is generally reserved for serious drug resistant gram-positive infections.

What is Primaxin IV?

PRIMAXIN I.V. (Imipenem and Cilastatin for Injection) is a sterile formulation of imipenem (a thienamycin antibiotic) and cilastatin sodium (the inhibitor of the renal dipeptidase, dehydropeptidase l), with sodium bicarbonate added as a buffer.

What is Imipenem (Primaxin)?

From Wikipedia, the free encyclopedia Imipenem (trade name Primaxin among others) is an intravenous β-lactam antibiotic discovered by Merck scientists Burton Christensen, William Leanza, and Kenneth Wildonger in the mid-1970s.

What is the difference between Primaxin IV and cilastatin?

Cilastatin helps imipenem work more effectively by preventing the breakdown of the antibiotic in the kidneys. Primaxin IV is a combination medicine used to treat severe infections of the lower respiratory tract, skin, stomach, or female reproductive organs.

What is the half-life of Primaxin?

intravenous infusion of PRIMAXIN I.V. range from 15 to 25 µg/mL for the 250 mg dose, from 31 to 49 µg/mL for the 500 mg dose, and from 56 to 88 µg/mL for the 1000 mg dose. The plasma half-life of each component is approximately 1 hour.